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Home/Compounds/CAS 68401-81-0
Formula C13H13N5O5S2MW 383.4Research-use catalog entryCOA/SDS by request

Ceftizoxime

CAS Number: 68401-81-0

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1 g
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Loading RDKit molecule structure...
InChIKey: NNULBSISHYWZJU-LLKWHZGFSA-NC13H13N5O5S2 | MW 383.4

Chemical Absolute Identifiers

CAS Number

68401-81-0

PubChem CID

6533629

Molecular Formula

C13H13N5O5S2

Molecular Weight

383.4 g/mol

Exact Mass

383.035811

InChIKey

NNULBSISHYWZJU-LLKWHZGFSA-N

IUPAC Name

(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

SMILES String

CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(N)n1

Physical Properties

Water Solubility

0.229 g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ceftizoxime (CAS 68401-81-0) is listed in the Advanced Chemicals portfolio, with molecular formula C13H13N5O5S2 and molecular weight 383. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays; Progesterone receptor (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 4.82

Experimental evidence source: ChEMBL

Progesterone receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.58

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Ceftizoxime

Names & Synonyms

CeftizoximaCeftizoximumsyn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, (6R-(6alpha,7beta(Z)))-
Show all synonyms
(6R,7R)-7-(((2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINOACETYL)AMINO)-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID(6R,7R)-7-((2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid7-(2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino)-8-oxo-5-thia-1-aza-bicyclo(4.2.0)oct-2-ene-2-carboxylic acid7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidceftizoximum alapivoxilumSKF 88373SK&F 8837325-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, (6R-(6-alpha,7-beta(Z)))-SK&F 88373 2EpocelinCeftizoximum [INN-Latin]Ceftizoxima [INN-Spanish]Ceftizoxime (INN)(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
External Identifiers
EC NUMBER: 685-309-4DSSTOX SUBSTANCE ID: DTXSID5022772CHEMBL ID: CHEMBL528CHEBI ID: CHEBI:553473UNII: C43C467DPEDRUGBANK ID: DB01332HMDB ID: HMDB0015427KEGG ID: C06890KEGG ID: D07658METABOLOMICS WORKBENCH ID: 43500NCI THESAURUS CODE: C61668PHARMGKB ID: PA164748758WIKIDATA ID: Q1082945
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c00983Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.PMID 39083648Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1016/j.ejmech.2021.114050An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a.PMID 34922190An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a.DOI 10.1016/j.drudis.2016.02.015DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.PMID 26948801DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
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Text Reference Cues

Show non-linked catalog cues

Non-public related references

Cefetamet Pivoxil HydrochlorideCAS 111696-23-2
Cefpodoxime ProxetilCAS 87239-81-4
CefiximeCAS 79350-37-1
CefdinirCAS 91832-40-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 111696-23-2Cefetamet Pivoxil HydrochlorideCAS 87239-81-4Cefpodoxime ProxetilCAS 79350-37-1CefiximeCAS 91832-40-5CefdinirCAS 102767-28-2LevetiracetamCAS 106308-44-5RufinamideCAS 107724-20-9EplerenoneCAS 25953-19-9CefazolinCAS 50370-12-2CefadroxilCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 68401-81-0

What are the key identifiers for Ceftizoxime (CAS 68401-81-0)?

Ceftizoxime is identified by CAS 68401-81-0, with molecular formula C13H13N5O5S2, molecular weight 383.4, InChIKey NNULBSISHYWZJU-LLKWHZGFSA-N.

Does CAS 68401-81-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor subfamily 1 group I member 2, Progesterone receptor, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 68401-81-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ceftizoxime?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 68401-81-0 available for quotation?

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