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Home/Compounds/CAS 70458-96-7
Formula C16H18FN3O3MW 319.33Research-use catalog entryCOA/SDS by request

Norfloxacin

CAS Number: 70458-96-7

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Loading RDKit molecule structure...
InChIKey: OGJPXUAPXNRGGI-UHFFFAOYSA-NC16H18FN3O3 | MW 319.33

Chemical Absolute Identifiers

CAS Number

70458-96-7

PubChem CID

4539

Molecular Formula

C16H18FN3O3

Molecular Weight

319.33 g/mol

Exact Mass

319.13322

InChIKey

OGJPXUAPXNRGGI-UHFFFAOYSA-N

IUPAC Name

1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

SMILES String

CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Norfloxacin (CAS 70458-96-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C16H18FN3O3 and molecular weight 319. 33 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: DNA gyrase (Escherichia coli) — 8 assays; Thyrotropin receptor (Homo sapiens) — 2 assays; DNA topoisomerase 2-beta (Homo sapiens) — 11 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 3 assays; Cannabinoid receptor 1 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

DNA gyrase

Escherichia coli · PROTEIN COMPLEX · 8 qualifying assays · 6 documents · best pChEMBL 6.22

Experimental evidence source: ChEMBL

Thyrotropin receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.8

Experimental evidence source: ChEMBL

DNA topoisomerase 2-beta

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 5 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Cannabinoid receptor 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, hydrogen fluoride, nitrogen oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

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  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Norfloxacin

Names & Synonyms

NoroxinNorfloxacineChibroxinBaccidalSebercim
Show all synonyms
NorfloxacinoFulgramNorfloxacinum1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acidNFLX1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-Utinor1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-MK366MK 366AM 0715
External Identifiers
EC NUMBER: 274-614-4DSSTOX SUBSTANCE ID: DTXSID7037680CHEMBL ID: CHEMBL9CHEBI ID: CHEBI:100246UNII: N0F8P22L1PDRUGBANK ID: DB01059HMDB ID: HMDB0015192KEGG ID: C06687KEGG ID: D00210METABOLOMICS WORKBENCH ID: 43297NCI THESAURUS CODE: C47638PHARMGKB ID: PA450654
Experimental Spectrum References
13C NMR Spectra15N NMR SpectraATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.bmcl.2024.129709Hydrazyl hydroxycoumarins as new potential conquerors towards Pseudomonas aeruginosa.DOI 10.1016/j.ejmech.2024.116219Novel aminothiazoximone-corbelled ethoxycarbonylpyrimidones with antibiofilm activity to conquer Gram-negative bacteria through potential multitargeting effects.DOI 10.1016/j.ejmech.2024.116266Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity.DOI 10.1016/j.ejmech.2024.116274Novel membrane-targeting isoxanthohumol-amine conjugates for combating methicillin-resistant Staphylococcus aureus (MRSA) infections.DOI 10.1016/j.ejmech.2024.116293Design, synthesis and antibacterial evaluation of low toxicity amphiphilic-cephalosporin derivatives.DOI 10.1016/j.ejmech.2024.116339Cajaninstilbene acid derivatives conjugated with siderophores of 3-hydroxypyridin-4(1H)-ones as novel antibacterial agents against Gram-negative bacteria based on the Trojan horse strategy.DOI 10.1016/j.ejmech.2024.116392Discovery of indolylacryloyl-derived oxacins as novel potential broad-spectrum antibacterial candidates.DOI 10.1016/j.ejmech.2024.116449Novel natural osthole-inspired amphiphiles as membrane targeting antibacterials against methicillin-resistant Staphylococcus aureus (MRSA).

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

PefloxacinCAS 70458-92-3
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrate (2:3)CAS 84294-96-2
Sarafloxacin HydrochlorideCAS 91296-87-6
FleroxacinCAS 79660-72-3
Piromidic AcidCAS 19562-30-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 70458-92-3PefloxacinCAS 84294-96-21,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrate (2:3)CAS 91296-87-6Sarafloxacin HydrochlorideCAS 79660-72-3FleroxacinCAS 19562-30-2Piromidic AcidCAS 100643-71-8DesloratadineCAS 106516-24-9SertindoleCAS 111974-69-7QuetiapineCAS 389-08-2Nalidixic AcidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 70458-96-7

What are the key identifiers for Norfloxacin (CAS 70458-96-7)?

Norfloxacin is identified by CAS 70458-96-7, with molecular formula C16H18FN3O3, molecular weight 319.33, InChIKey OGJPXUAPXNRGGI-UHFFFAOYSA-N.

Does CAS 70458-96-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with DNA gyrase, Thyrotropin receptor, DNA topoisomerase 2-beta, Alpha-1A adrenergic receptor, Cannabinoid receptor 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 70458-96-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Norfloxacin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 70458-96-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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