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Home/Compounds/CAS 71486-22-1
Formula C45H54N4O8MW 778.9Research-use catalog entryCOA/SDS by request

Vinorelbine

CAS Number: 71486-22-1

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Loading RDKit molecule structure...
InChIKey: GBABOYUKABKIAF-IELIFDKJSA-NC45H54N4O8 | MW 778.9

Chemical Absolute Identifiers

CAS Number

71486-22-1

PubChem CID

5311497

Molecular Formula

C45H54N4O8

Molecular Weight

778.9 g/mol

Exact Mass

778.394165

InChIKey

GBABOYUKABKIAF-IELIFDKJSA-N

IUPAC Name

methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(12S,14R)-16-ethyl-12-methoxycarbonyl-1,10-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate

SMILES String

CCC1=C[C@@H]2CN(C1)Cc1c([nH]c3ccccc13)[C@@](C(=O)OC)(c1cc3c(cc1OC)N(C)[C@H]1[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]4(CC)C=CCN5CC[C@]31[C@@H]54)C2

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Vinorelbine (CAS 71486-22-1) is listed in the Life Science portfolio, with molecular formula C45H54N4O8 and molecular weight 778. 90 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: 4'-phosphopantetheinyl transferase ffp (Bacillus subtilis) — 3 assays; ATP-dependent translocase ABCB1 (Homo sapiens) — 3 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 2 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

4'-phosphopantetheinyl transferase ffp

Bacillus subtilis · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 4.85

Experimental evidence source: ChEMBL

ATP-dependent translocase ABCB1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Vinorelbine

Names & Synonyms

VinorelbinaVinorelbinumNavelbinNor-5'-anhydrovinblastineC'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy-
Show all synonyms
5' Nor anhydrovinblastine5'-nor-anhydrovinblastineDihydroxydeoxynorvinkaleukoblastine3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastineExelbineVinorelbine (INN)Navelbine (TN)KW-2307 baseVinorelbinum [Latin]Vinorelbina [Spanish]Navelbine baseVINORELBINE [INN]Vinorelbine [INN:BAN]KW 2307 baseVinorelbine?
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID8040640CHEMBL ID: CHEMBL553025CHEBI ID: CHEBI:480999UNII: Q6C979R91YDRUGBANK ID: DB00361KEGG ID: D01935KEGG ID: D08680METABOLOMICS WORKBENCH ID: 145105NCI THESAURUS CODE: C1275PHARMGKB ID: PA451881RXCUI: 39541WIKIDATA ID: Q420532
Experimental Spectrum References
UV Spectra
Literature & Patent References
DOI 10.1016/j.bmcl.2025.130096Applications of innovative synthetic strategies in anticancer drug discovery: The driving force of new chemical reactions.DOI 10.1016/j.ejmech.2024.117130Design, synthesis and biological evaluation of novel diaryl-substituted fused nitrogen heterocycles as tubulin polymerization inhibitors to overcome multidrug resistance in vitro and in vivo.PMID 39662283Design, synthesis and biological evaluation of novel diaryl-substituted fused nitrogen heterocycles as tubulin polymerization inhibitors to overcome multidrug resistance in vitro and in vivo.PMID 39798856Applications of innovative synthetic strategies in anticancer drug discovery: The driving force of new chemical reactions.DOI 10.1016/j.ejmech.2024.116617Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents.DOI 10.1021/acs.jmedchem.3c01920Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance.DOI 10.1021/acs.jmedchem.4c00388Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.DOI 10.1039/d3md00677hIndole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

NavelbineCAS 125317-39-7
Vincristine SulfateCAS 2068-78-2
(+)-CatharanthineCAS 2468-21-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 125317-39-7NavelbineCAS 2068-78-2Vincristine SulfateCAS 21829-25-4NifedipineCAS 100643-71-8DesloratadineCAS 112574-44-4NitrofurazoneCAS 302-79-4Retinoic AcidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 71486-22-1

What are the key identifiers for Vinorelbine (CAS 71486-22-1)?

Vinorelbine is identified by CAS 71486-22-1, with molecular formula C45H54N4O8, molecular weight 778.9, InChIKey GBABOYUKABKIAF-IELIFDKJSA-N.

Does CAS 71486-22-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with 4'-phosphopantetheinyl transferase ffp, ATP-dependent translocase ABCB1, Alpha-1A adrenergic receptor, Muscarinic acetylcholine receptor M1, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 71486-22-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Vinorelbine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 71486-22-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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