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Home/Compounds/CAS 71989-23-6
Formula C21H23NO4MW 353.4Research-use catalog entryCOA/SDS by request

N-Fmoc-L-isoleucine

CAS Number: 71989-23-6

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Loading RDKit molecule structure...
InChIKey: QXVFEIPAZSXRGM-DJJJIMSYSA-NC21H23NO4 | MW 353.4

Chemical Absolute Identifiers

CAS Number

71989-23-6

PubChem CID

2724629

Molecular Formula

C21H23NO4

Molecular Weight

353.4 g/mol

Exact Mass

353.162708

InChIKey

QXVFEIPAZSXRGM-DJJJIMSYSA-N

IUPAC Name

(2S,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylpentanoic acid

SMILES String

CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

N-Fmoc-L-isoleucine (CAS 71989-23-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C21H23NO4 and molecular weight 353. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Aldehyde dehydrogenase 1A1 (Homo sapiens) — 2 assays; Cellular tumor antigen p53 (Homo sapiens) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Aldehyde dehydrogenase 1A1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.35

Experimental evidence source: ChEMBL

Cellular tumor antigen p53

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.5

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.5

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

N-Fmoc-L-isoleucine

Names & Synonyms

Fmoc-Ile-OHFmoc-L-isoleucineFmoc-L-Ile-OHFmoc-lle-OHN-(9-Fluorenylmethoxycarbonyl)-L-isoleucine
Show all synonyms
(2S,3S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoic acid(2S,3S)-2-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-3-METHYLPENTANOIC ACIDL-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-Fmoc-D-Ile-OH(2S,3S)-2-[(fluoren-9-ylmethoxy)carbonylamino]-3-methylpentanoic acidFMOC-ILEFMOC-L-ILE9-FLUORENYLMETHOXYCARBONYL-L-ISOLEUCINEN-.alpha.-Fmoc-L-isoleucine(((9H-fluoren-9-yl)methoxy)carbonyl)-L-isoleucine(2S,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl-pentanoic acidFmoc-Ile-OH, >=98.0% (T)F0294N-(Fluoren-9-ylmethoxycarbonyl)-L-isoleucine
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID801315561CHEMBL ID: CHEMBL560020CHEBI ID: CHEBI:228607UNII: 24UNH77L7AWIKIDATA ID: Q76145910
Experimental Spectrum References
13C NMR Spectra — Sigma-Aldrich Co. LLC.1H NMR Spectra — Sigma-Aldrich Co. LLC.ATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Bio-Rad Laboratories, Inc.
Literature & Patent References
DOI 10.1021/acsmedchemlett.1c00721Development of Low-Molecular-Weight Compounds Targeting the Cancer-Associated KLF5 Transcription Factor.PMID 35450365Development of Low-Molecular-Weight Compounds Targeting the Cancer-Associated KLF5 Transcription Factor.DOI 10.1021/acs.jmedchem.9b02119Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.PMID 32608236Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.DOI 10.1016/j.bmcl.2018.09.034Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques.PMID 30301675Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques.DOI 10.1016/j.ejmech.2008.11.008Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents.PMID 19110343Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

N-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-alanineCAS 35661-39-3
O-(tert-butyl)-N-((9H-fluoren-9-ylmethoxy)carbonyl)-L-serineCAS 71989-33-8
Fmoc-Pro-OHCAS 71989-31-6
Ethyl 1-benzylpiperidine-4-carboxylateCAS 24228-40-8
Ethyl 2-methylacetoacetateCAS 609-14-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 35661-39-3N-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-alanineCAS 71989-33-8O-(tert-butyl)-N-((9H-fluoren-9-ylmethoxy)carbonyl)-L-serineCAS 71989-31-6Fmoc-Pro-OHCAS 82911-69-1N-(9-Fluorenylmethoxycarbonyloxy)succinimideCAS 28920-43-69-Fluorenylmethyl chloroformateCAS 26049-94-5(3S)-3-Benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanoneCAS 112574-44-4NitrofurazoneCAS 117-79-32-AminoanthraquinoneCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 71989-23-6

What are the key identifiers for N-Fmoc-L-isoleucine (CAS 71989-23-6)?

N-Fmoc-L-isoleucine is identified by CAS 71989-23-6, with molecular formula C21H23NO4, molecular weight 353.4, InChIKey QXVFEIPAZSXRGM-DJJJIMSYSA-N.

Does CAS 71989-23-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Aldehyde dehydrogenase 1A1, Cellular tumor antigen p53, Cytochrome P450 3A4. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 71989-23-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for N-Fmoc-L-isoleucine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 71989-23-6 available for quotation?

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