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Home/Compounds/CAS 74-11-3
Formula C7H5ClO2MW 156.56Research-use catalog entryCOA/SDS by request

4-Chlorobenzoic Acid

CAS Number: 74-11-3

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Available options

Available Options

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1 kg
Purity
98%
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Loading RDKit molecule structure...
InChIKey: XRHGYUZYPHTUJZ-UHFFFAOYSA-NC7H5ClO2 | MW 156.56

Chemical Absolute Identifiers

CAS Number

74-11-3

PubChem CID

6318

Molecular Formula

C7H5ClO2

Molecular Weight

156.56 g/mol

Exact Mass

155.997807

InChIKey

XRHGYUZYPHTUJZ-UHFFFAOYSA-N

SMILES String

C1=CC(=CC=C1C(=O)O)Cl

Physical Properties

Appearance

Triclinic crystals or light fluffy white powder. (NTP, 1992)

Flash Point

238.0 °C

pKa

3.98–4.03

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

4-Chlorobenzoic Acid (CAS 74-11-3) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C7H5ClO2 and molecular weight 156. 56 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Thyrotropin receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Thyrotropin receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.4

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

4-Chlorobenzoic Acid

Names & Synonyms

P-CHLOROBENZOIC ACIDBenzoic acid, 4-chloro-Chlorodracylic acidp-Chlorbenzoic acidpara-Chlorobenzoic acid
Show all synonyms
Benzoic acid, p-chloro-4-CHLORO-BENZOIC ACIDp-CarboxychlorobenzeneAcido p-clorobenzoicoAcido p-clorobenzoico [Italian]4-chloro benzoic acid4-chlorobenzoic acid-alpha-13c4-ChlorobenzoicacidCCRIS 5994HSDB 6019MycosidNCIOpen2_004782S3 (4-chlorobenzoic acid)4-09-00-00973 (Beilstein Handbook Reference)
External Identifiers
EC NUMBER: 200-805-9EC NUMBER: 695-032-0DSSTOX SUBSTANCE ID: DTXSID9024772CHEMBL ID: CHEMBL618CHEBI ID: CHEBI:30747UNII: IC7888DF4LDRUGBANK ID: DB03728HMDB ID: HMDB0246393ICSC NUMBER: 0503KEGG ID: C02370METABOLOMICS WORKBENCH ID: 52012WIKIDATA ID: Q2235989bmse000438
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR SpectraFTIR SpectraRaman SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.9b01746Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo.PMID 32031798Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo.DOI 10.1016/j.bmc.2011.10.013Benzenepolycarboxylic acids with potential anti-hemorrhagic properties and structure-activity relationships.PMID 22047800Benzenepolycarboxylic acids with potential anti-hemorrhagic properties and structure-activity relationships.DOI 10.1007/s00044-009-9162-3Study on the quantitative structuretoxicity relationships of benzoic acid derivatives in rats via oral LD50DOI 10.1021/jm950589qComparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.PMID 8667357Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.DOI 10.1021/jm00072a012QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4-Bromobenzoic acidCAS 586-76-5
4-(Aminomethyl)Benzoic AcidCAS 56-91-7
4-Phenoxybenzoic acidCAS 2215-77-2
1-(p-Chlorophenyl)cyclobutanecarboxylic acidCAS 50921-39-6
2,6-Dichlorobenzoic acidCAS 50-30-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 586-76-54-Bromobenzoic acidCAS 56-91-74-(Aminomethyl)Benzoic AcidCAS 2215-77-24-Phenoxybenzoic acidCAS 50921-39-61-(p-Chlorophenyl)cyclobutanecarboxylic acidCAS 50-30-62,6-Dichlorobenzoic acidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 74-11-3

What are the key identifiers for 4-Chlorobenzoic Acid (CAS 74-11-3)?

4-Chlorobenzoic Acid is identified by CAS 74-11-3, with molecular formula C7H5ClO2, molecular weight 156.56, InChIKey XRHGYUZYPHTUJZ-UHFFFAOYSA-N.

Does CAS 74-11-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Thyrotropin receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 74-11-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 4-Chlorobenzoic Acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 74-11-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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