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Home/Compounds/CAS 760981-83-7
Formula C43H65FN6O10MW 845Research-use catalog entryCOA/SDS by request

Solithromycin

CAS Number: 760981-83-7

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Purity
98%
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Purity
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250 mg
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50 mg
Purity
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Loading RDKit molecule structure...
InChIKey: IXXFZUPTQVDPPK-ZAWHAJPISA-NC43H65FN6O10 | MW 845

Chemical Absolute Identifiers

CAS Number

760981-83-7

PubChem CID

25242512

Molecular Formula

C43H65FN6O10

Molecular Weight

845 g/mol

Exact Mass

844.47462

InChIKey

IXXFZUPTQVDPPK-ZAWHAJPISA-N

IUPAC Name

(1S,2R,5S,7R,8R,9R,11R,13R,14R)-15-[4-[4-(3-aminophenyl)triazol-1-yl]butyl]-8-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-5-fluoro-9-methoxy-1,5,7,9,11,13-hexamethyl-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone

SMILES String

CC[C@H]1OC(=O)[C@@](C)(F)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCCn3cc(-c4cccc(N)c4)nn3)C(=O)O[C@]12C

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Solithromycin (CAS 760981-83-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C43H65FN6O10 and molecular weight 845. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Solithromycin

Names & Synonyms

SolitheraCEM 101solithromycinesolitromicinaOP 1068
Show all synonyms
solithromycinum(3AR,4R,7S,9R,10R,11R,13R,15R,15AR)-1-(4-(4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl)butyl)-4-ethyl-7-fluoro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-trideoxy-(dimethylamino)-Solithromycin [USAN]Solithromycin [USAN:INN]Solithromycin?EM1Solithromycin (Standard)SOLITHROMYCIN [INN]SOLITHROMYCIN [JAN]SOLITHROMYCIN [WHO-DD]compound 3 [PMID: 30258539](3AR,4R,7S,9R,10R,11R,13R,15R,15AR)-1-(4-(4-(3-AMINOPHENYL)-1H-1,2,3-TRIAZOL-1-YL)BUTYL)-4-ETHYL-7-FLUORO-11-METHOXY-3A,7,9,11,13,15-HEXAMETHYL-10-((TRIDEOXY-(DIMETHYLAMINO)-(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID501028410CHEMBL ID: CHEMBL1232510CHEBI ID: CHEBI:230261UNII: 9U1ETH79CKDRUGBANK ID: DB09308METABOLOMICS WORKBENCH ID: 152326NCI THESAURUS CODE: C152386PHARMGKB ID: PA166165147WIKIDATA ID: Q7558263
Literature & Patent References
DOI 10.1016/j.bmc.2023.117381Synthesis of novobiocin derivatives and evaluation of their antigonococcal activity and pharmacokinetics.PMID 37506559Synthesis of novobiocin derivatives and evaluation of their antigonococcal activity and pharmacokinetics.DOI 10.1016/j.ejmech.2022.114213Alternative approaches utilizing click chemistry to develop next-generation analogs of solithromycin.PMID 35240514Alternative approaches utilizing click chemistry to develop next-generation analogs of solithromycin.DOI 10.1016/j.bmc.2021.115995Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33477021Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.DOI 10.1021/acs.jmedchem.9b01183Kinetic Target-Guided Synthesis: Reaching the Age of Maturity.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Erythromycin, cyclic 11,12-carbonateCAS 55224-05-0
ErythromycinCAS 114-07-8
RoxithromycinCAS 80214-83-1
9-Deoxo-9a-aza-9a-homoerythromycin ACAS 76801-85-9
DirithromycinCAS 62013-04-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 55224-05-0Erythromycin, cyclic 11,12-carbonateCAS 100-88-9CyclamateCAS 1000787-75-6TegobuvirCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 760981-83-7

What are the key identifiers for Solithromycin (CAS 760981-83-7)?

Solithromycin is identified by CAS 760981-83-7, with molecular formula C43H65FN6O10, molecular weight 845, InChIKey IXXFZUPTQVDPPK-ZAWHAJPISA-N.

Does CAS 760981-83-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 760981-83-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Solithromycin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 760981-83-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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