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Home/Compounds/CAS 77-60-1
Formula C27H44O3MW 416.6Research-use catalog entryCOA/SDS by request

Tigogenin

CAS Number: 77-60-1

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Loading RDKit molecule structure...
InChIKey: GMBQZIIUCVWOCD-MFRNJXNGSA-NC27H44O3 | MW 416.6

Chemical Absolute Identifiers

CAS Number

77-60-1

PubChem CID

99516

Molecular Formula

C27H44O3

Molecular Weight

416.6 g/mol

Exact Mass

416.329045

InChIKey

GMBQZIIUCVWOCD-MFRNJXNGSA-N

IUPAC Name

(1R,2S,4S,5'R,6R,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-ol

SMILES String

C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Tigogenin (CAS 77-60-1) is listed in the Advanced Chemicals portfolio, with molecular formula C27H44O3 and molecular weight 416. 60 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Chemical BiologySynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: UDP-glucuronosyltransferase 1A4 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

UDP-glucuronosyltransferase 1A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

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Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

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  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Tigogenin

Names & Synonyms

5-alpha-Spirostan-3-beta-olSpirostan-3-ol, (3beta,5alpha,25R)-(1R,2S,4S,5'R,6R,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro(5-oxapentacyclo(10.8.0.02,9.04,8.013,18)icosane-6,2'-oxane)-16-ol(25R)-5alpha-Spirostan-3beta-olTICOGENIN
Show all synonyms
(5alpha,25R)-Spirostan-3beta-ol(2aS,2'R,4S,5'R,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-Tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-olA1CGZ(2aS,4S,5'R,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-Tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-olSpirostan-3-ol, (3b,5a,25R)-(25R)-5.alpha.-Spirostan-3.beta.-ol5-epi-sarsasapogeninTigogenin (Standard)(3-beta,5-alpha,25R)-Spirostan-3-ol(3.BETA.,5.BETA.,25R)-SPIROSTAN-3-OLTIGOGENIN [MI](3beta,5alpha,25R)-spirostan-3-ol5alpha-Spirostan-3beta-ol, (25R)-(3-beta,5alpha,25R)-spirostan-3-ol
External Identifiers
EC NUMBER: 201-041-9DSSTOX SUBSTANCE ID: DTXSID40903920CHEMBL ID: CHEMBL43871CHEBI ID: CHEBI:9595UNII: 4SMU15RR44KEGG ID: C08914METABOLOMICS WORKBENCH ID: 35103WIKIDATA ID: Q27108442
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1124/mol.112.084152Structure-based identification of OATP1B1/3 inhibitors.PMID 23571415Structure-based identification of OATP1B1/3 inhibitors.DOI 10.1016/j.bmcl.2011.03.092Synthesis and antifungal activity of functionalized 2,3-spirostane isomers.DOI 10.1021/np2003484Microbial transformations of diosgenin by the white-rot basidiomycete Coriolus versicolor.PMID 21489791Synthesis and antifungal activity of functionalized 2,3-spirostane isomers.PMID 21985022Microbial transformations of diosgenin by the white-rot basidiomycete Coriolus versicolor.DOI 10.1021/jm020397cPharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity.PMID 12699380Pharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

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  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-2-[(1S,2S,4S,5'S,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triolCAS 87480-46-4
DigitoninCAS 11024-24-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 118090-09-81,3-benzothiazole-2-thiolCAS 122-11-2SulfadimethoxineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 77-60-1

What are the key identifiers for Tigogenin (CAS 77-60-1)?

Tigogenin is identified by CAS 77-60-1, with molecular formula C27H44O3, molecular weight 416.6, InChIKey GMBQZIIUCVWOCD-MFRNJXNGSA-N.

Does CAS 77-60-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with UDP-glucuronosyltransferase 1A4. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 77-60-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Tigogenin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 77-60-1 available for quotation?

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