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Home/Compounds/CAS 77-92-9
Formula C6H8O7MW 192.12Research-use catalog entryCOA/SDS by request

Citric Acid

CAS Number: 77-92-9

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Loading RDKit molecule structure...
InChIKey: KRKNYBCHXYNGOX-UHFFFAOYSA-NC6H8O7 | MW 192.12

Chemical Absolute Identifiers

CAS Number

77-92-9

PubChem CID

311

Molecular Formula

C6H8O7

Molecular Weight

192.12 g/mol

Exact Mass

192.027003

InChIKey

KRKNYBCHXYNGOX-UHFFFAOYSA-N

IUPAC Name

2-hydroxypropane-1,2,3-tricarboxylic acid

SMILES String

C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Physical Properties

Melting Point

153.0 °C

Flash Point

1.0 °C

pKa

2.79

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Citric Acid (CAS 77-92-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C6H8O7 and molecular weight 192. 12 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays; Estrogen receptor (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 2 assays; Nuclear factor erythroid 2-related factor 2 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Estrogen receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Nuclear factor erythroid 2-related factor 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Citric Acid

Names & Synonyms

Citric acid, anhydrousAcilettenAnhydrous citric acidCitroCitretten
Show all synonyms
Citric acid anhydrousChemfillHydrocerol A1,2,3-Propanetricarboxylic acid, 2-hydroxy-2-hydroxy-1,2,3-propanetricarboxylic acidKyselina citronova2-Hydroxytricarballylic acidbeta-Hydroxytricarballylic acid3-Carboxy-3-hydroxypentane-1,5-dioic acidFEMA No. 2306FEMA Number 2306Citric acid,anhydrousCitricum acidumCitric acid monoglyceride
External Identifiers
EC NUMBER: 201-069-1EC NUMBER: 680-681-4EC NUMBER: 920-306-6EC NUMBER: 921-454-4DSSTOX SUBSTANCE ID: DTXSID3020332CHEMBL ID: CHEMBL1261CHEBI ID: CHEBI:30769UNII: XF417D3PSLDRUGBANK ID: DB04272HMDB ID: HMDB0000094ICSC NUMBER: 0855KEGG ID: C00158KEGG ID: D00037METABOLOMICS WORKBENCH ID: 37071NCI THESAURUS CODE: C80088PHARMGKB ID: PA449021RXCUI: 21183RXCUI: 221946WIKIDATA ID: Q159683
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Bio-Rad Laboratories, Inc.
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117163Unravelling the potential of natural chelating agents in the control of Staphylococcus aureus and Pseudomonas aeruginosa biofilms.DOI 10.1021/acs.jmedchem.4c01542Discovery of a Novel Selective and Cell-Active N<sup>6</sup>-Methyladenosine RNA Demethylase ALKBH5 Inhibitor.PMID 39700872Unravelling the potential of natural chelating agents in the control of Staphylococcus aureus and Pseudomonas aeruginosa biofilms.PMID 39925002Discovery of a Novel Selective and Cell-Active N<sup>6</sup>-Methyladenosine RNA Demethylase ALKBH5 Inhibitor.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1021/acs.jmedchem.0c01762Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.DOI 10.1021/acs.jmedchem.1c00308Crystal Structures of Metallo-β-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(2R)-3-bromo-2-hydroxy-2-methylpropanoic acidCAS 261904-39-6
Glutaric AcidCAS 110-94-1
Suberic acidCAS 505-48-6
Aminoisobutyric acidCAS 62-57-7
3-(Tert-butoxy)-3-oxopropanoic acidCAS 40052-13-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 112574-44-4NitrofurazoneCAS 21829-25-4NifedipineCAS 22204-53-1NaproxenCAS 59-67-6Nicotinic AcidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 77-92-9

What are the key identifiers for Citric Acid (CAS 77-92-9)?

Citric Acid is identified by CAS 77-92-9, with molecular formula C6H8O7, molecular weight 192.12, InChIKey KRKNYBCHXYNGOX-UHFFFAOYSA-N.

Does CAS 77-92-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, Alpha-1A adrenergic receptor, Estrogen receptor, Muscarinic acetylcholine receptor M1, Nuclear factor erythroid 2-related factor 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 77-92-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Citric Acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 77-92-9 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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