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Home/Compounds/CAS 773-76-2
Formula C9H5Cl2NOMW 214.04Research-use catalog entryCOA/SDS by request

Chloroxine

CAS Number: 773-76-2

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Available Options

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100 g
Purity
98%
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100 mg
Purity
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25 g
Purity
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5 g
Purity
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Loading RDKit molecule structure...
InChIKey: WDFKMLRRRCGAKS-UHFFFAOYSA-NC9H5Cl2NO | MW 214.04

Chemical Absolute Identifiers

CAS Number

773-76-2

PubChem CID

2722

Molecular Formula

C9H5Cl2NO

Molecular Weight

214.04 g/mol

Exact Mass

212.974819

InChIKey

WDFKMLRRRCGAKS-UHFFFAOYSA-N

IUPAC Name

5,7-dichloroquinolin-8-ol

SMILES String

C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1

Physical Properties

Melting Point

179.5 °C

Water Solubility

0.138 g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Chloroxine (CAS 773-76-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C9H5Cl2NO and molecular weight 214. 04 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor ROR-gamma (Mus musculus) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 3 assays; Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens) — 2 assays; Matrix metalloproteinase-14 (Homo sapiens) — 2 assays; Cellular tumor antigen p53 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor ROR-gamma

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.1

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 6.35

Experimental evidence source: ChEMBL

Polyunsaturated fatty acid lipoxygenase ALOX12

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6

Experimental evidence source: ChEMBL

Matrix metalloproteinase-14

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.62

Experimental evidence source: ChEMBL

Cellular tumor antigen p53

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.5

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Chloroxine

Names & Synonyms

5,7-Dichloro-8-hydroxyquinoline5,7-Dichloro-8-quinolinolCapitrolChlorquinolQuixalin
Show all synonyms
Dichlorohydroxyquinoline5,7-Dichlorooxine5,7-Dichloroxine8-QUINOLINOL, 5,7-DICHLORO-5,7-Dichloro-8-oxyquinoline5,7-Dichlor-8-hydroxychinolindichloroquineDichloroxinChloroxyquinolineDichloroquinolinolClofuzidEndiaronChlofucidDikhloroskin
External Identifiers
EC NUMBER: 212-258-3DSSTOX SUBSTANCE ID: DTXSID5022801CHEMBL ID: CHEMBL1200596CHEBI ID: CHEBI:59477UNII: 2I8BD50I8BDRUGBANK ID: DB01243HMDB ID: HMDB0015373KEGG ID: D03472METABOLOMICS WORKBENCH ID: 43451NCI THESAURUS CODE: C47446PHARMGKB ID: PA164754879WIKIDATA ID: Q12029435
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR SpectraFTIR SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116833Drug repurposing against antibiotic resistant bacterial pathogens.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 39243454Drug repurposing against antibiotic resistant bacterial pathogens.DOI 10.1016/j.bmc.2023.117289Identification of small molecule inhibitors against MMP-14 via High-Throughput screening.DOI 10.1021/acs.jmedchem.3c00171Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase-1 Re-sensitizing Multidrug-Resistant Bacteria for Carbapenems.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37094433Identification of small molecule inhibitors against MMP-14 via High-Throughput screening.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

5-Chloro-8-hydroxyquinolineCAS 130-16-5
ChlorquinaldolCAS 72-80-0
NitroxolineCAS 4008-48-4
ProthionamideCAS 14222-60-7
2-ethylpyridine-4-carboximidothioic acidCAS 536-33-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 130-16-55-Chloro-8-hydroxyquinolineCAS 72-80-0ChlorquinaldolCAS 521-74-4BroxyquinolineCAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 50-65-7NiclosamideCAS 154-42-72-amino-7H-purine-6-thiolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 773-76-2

What are the key identifiers for Chloroxine (CAS 773-76-2)?

Chloroxine is identified by CAS 773-76-2, with molecular formula C9H5Cl2NO, molecular weight 214.04, InChIKey WDFKMLRRRCGAKS-UHFFFAOYSA-N.

Does CAS 773-76-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor ROR-gamma, Tyrosyl-DNA phosphodiesterase 1, Polyunsaturated fatty acid lipoxygenase ALOX12, Matrix metalloproteinase-14, Cellular tumor antigen p53. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 773-76-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Chloroxine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 773-76-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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