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Home/Compounds/CAS 80214-83-1
Formula C41H76N2O15MW 837Research-use catalog entryCOA/SDS by request

Roxithromycin

CAS Number: 80214-83-1

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Loading RDKit molecule structure...
InChIKey: RXZBMPWDPOLZGW-XMRMVWPWSA-NC41H76N2O15 | MW 837

Chemical Absolute Identifiers

CAS Number

80214-83-1

PubChem CID

6915744

Molecular Formula

C41H76N2O15

Molecular Weight

837 g/mol

Exact Mass

836.52457

InChIKey

RXZBMPWDPOLZGW-XMRMVWPWSA-N

IUPAC Name

(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one

SMILES String

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)/C(=N\OCOCCOC)[C@H](C)[C@@H](O)[C@]1(C)O

Physical Properties

pKa

9.27

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Roxithromycin (CAS 80214-83-1) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C41H76N2O15 and molecular weight 837. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 3 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 1A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Roxithromycin

Names & Synonyms

RulideRulidRU 28965RU 965(9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)
Show all synonyms
Erythromycin, 9-(O-((2-methoxyethoxy)methyl)oxime), (9E)-InfectoroxitErythromycin, 9-[O-[(2-methoxyethoxy)methyl]oxime], (9E)-Roxi-paed 1A PharmaRoxitromycinRoxitromycineRU9659-(2',5'-Dioxahexyloxyimino)erythromycin(9E)-Erythromycin, 9-(O-((2-methoxyethoxy)methyl)oxime)RoxithromycineRoxithromycinumRoxitromicinaErythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)9-(O-((2-Methoxyethoxy)methyl)oxime)erythromycinErythromycin 9-[O-[(2-methoxyethoxy)methyl]oxime]
External Identifiers
EC NUMBER: 617-007-5DSSTOX SUBSTANCE ID: DTXSID8041117CHEMBL ID: CHEMBL1214185CHEBI ID: CHEBI:48844UNII: 21KOF230FADRUGBANK ID: DB00778KEGG ID: C13173KEGG ID: D01710METABOLOMICS WORKBENCH ID: 43073NCI THESAURUS CODE: C818PHARMGKB ID: PA164750505WIKIDATA ID: Q424037
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2DOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

ErythromycinCAS 114-07-8
DirithromycinCAS 62013-04-1
9-Deoxo-9a-aza-9a-homoerythromycin ACAS 76801-85-9
Erythromycin, cyclic 11,12-carbonateCAS 55224-05-0
TulathromycinCAS 217500-96-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 114-07-8ErythromycinCAS 62013-04-1DirithromycinCAS 76801-85-99-Deoxo-9a-aza-9a-homoerythromycin ACAS 55224-05-0Erythromycin, cyclic 11,12-carbonateCAS 217500-96-4TulathromycinCAS 107724-20-9EplerenoneCAS 1231929-97-7AbemaciclibCAS 1156-19-0TolazamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 80214-83-1

What are the key identifiers for Roxithromycin (CAS 80214-83-1)?

Roxithromycin is identified by CAS 80214-83-1, with molecular formula C41H76N2O15, molecular weight 837, InChIKey RXZBMPWDPOLZGW-XMRMVWPWSA-N.

Does CAS 80214-83-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor subfamily 1 group I member 2, 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 80214-83-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Roxithromycin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 80214-83-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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