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Home/Compounds/CAS 81-07-2
Formula C7H5NO3SMW 183.19Research-use catalog entryCOA/SDS by request

Saccharin

CAS Number: 81-07-2

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Available options

Available Options

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1 kg
Purity
98%
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100 g
Purity
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500 g
Purity
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Loading RDKit molecule structure...
InChIKey: CVHZOJJKTDOEJC-UHFFFAOYSA-NC7H5NO3S | MW 183.19

Chemical Absolute Identifiers

CAS Number

81-07-2

PubChem CID

5143

Molecular Formula

C7H5NO3S

Molecular Weight

183.19 g/mol

Exact Mass

182.999014

InChIKey

CVHZOJJKTDOEJC-UHFFFAOYSA-N

IUPAC Name

1,1-dioxo-1,2-benzothiazol-3-one

SMILES String

C1=CC=C2C(=C1)C(=O)NS2(=O)=O

Physical Properties

Appearance

Saccharin (manufacturing) appears as white crystals. Odorless or faintly aromatic odor. Sweet taste. (NTP, 1992)

Melting Point

224.0 °C

Density

0.828 g/cm³

pKa

1.31

Show more physical data

Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Saccharin (CAS 81-07-2) is listed in the Advanced Chemicals portfolio, with molecular formula C7H5NO3S and molecular weight 183. 19 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Carbonic anhydrase 7 (Homo sapiens) — 3 assays; Alpha carbonic anhydrase (Stylophora pistillata) — 2 assays; Carbonic anhydrase 9 (Homo sapiens) — 11 assays; Carbonic anhydrase 12 (Homo sapiens) — 8 assays; Carbonic anhydrase 6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Carbonic anhydrase 7

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

Alpha carbonic anhydrase

Stylophora pistillata · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.39

Experimental evidence source: ChEMBL

Carbonic anhydrase 9

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 11 documents · best pChEMBL 7

Experimental evidence source: ChEMBL

Carbonic anhydrase 12

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 8 documents · best pChEMBL 6.2

Experimental evidence source: ChEMBL

Carbonic anhydrase 6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.03

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Saccharin

Names & Synonyms

o-Benzoic sulfimideo-SulfobenzimideSaccharineSaccharimideBenzosulfimide
Show all synonyms
Garantoseo-BenzosulfimideBenzoic sulfimideBenzosulphimideSaccharinolSaccharinoseSaccharin insolubleHermesetasSaccharolGlucidGlusideSaccharin acid1,2-Benzisothiazol-3(2H)-one, 1,1-dioxideBenzoic sulphimideBenzosulfinide
External Identifiers
EC NUMBER: 201-321-0DSSTOX SUBSTANCE ID: DTXSID5021251CHEMBL ID: CHEMBL310671CHEBI ID: CHEBI:32111UNII: FST467XS7DDRUGBANK ID: DB12418HMDB ID: HMDB0029723KEGG ID: C12283KEGG ID: D01085METABOLOMICS WORKBENCH ID: 44013NCI THESAURUS CODE: C76515RXCUI: 9509WIKIDATA ID: Q191381
Experimental Spectrum References
13C NMR Spectra15N NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral ResearchVapor Phase IR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116170pH regulators and their inhibitors in tumor microenvironment.DOI 10.1021/acs.jmedchem.4c01512Investigating Active Site Binding of Ligands to High and Low Activity Carbonic Anhydrase Enzymes Using Native Mass Spectrometry.PMID 38308950pH regulators and their inhibitors in tumor microenvironment.PMID 39161321Investigating Active Site Binding of Ligands to High and Low Activity Carbonic Anhydrase Enzymes Using Native Mass Spectrometry.DOI 10.1021/acs.jmedchem.2c00336<i>N</i>-Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction.PMID 35786925<i>N</i>-Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

5-AminosaccharinCAS 22094-61-7
6-AminosaccharinCAS 22094-62-8
5-Bromobenzo[d]isothiazol-3(2H)-one 1,1-dioxideCAS 29632-82-4
6-Bromo-2,3-dihydro-1,2-benzothiazole-1,1,3-trioneCAS 62473-92-1
6-NitrosaccharinCAS 22952-24-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 22094-61-75-AminosaccharinCAS 22094-62-86-AminosaccharinCAS 29632-82-45-Bromobenzo[d]isothiazol-3(2H)-one 1,1-dioxideCAS 62473-92-16-Bromo-2,3-dihydro-1,2-benzothiazole-1,1,3-trioneCAS 22952-24-56-NitrosaccharinCAS 68291-97-4ZonisamideCAS 169590-42-5CelecoxibCAS 14949-00-95-Amino-1,3,4-thiadiazole-2-sulfonamideCAS 181695-72-7ValdecoxibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 81-07-2

What are the key identifiers for Saccharin (CAS 81-07-2)?

Saccharin is identified by CAS 81-07-2, with molecular formula C7H5NO3S, molecular weight 183.19, InChIKey CVHZOJJKTDOEJC-UHFFFAOYSA-N.

Does CAS 81-07-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Carbonic anhydrase 7, Alpha carbonic anhydrase, Carbonic anhydrase 9, Carbonic anhydrase 12, Carbonic anhydrase 6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 81-07-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Saccharin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 81-07-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.