Research chemical
CAS Number: 843663-66-1
Product details
For laboratory research and professional procurement workflows.
PubChem CID
5388906
Exact Mass
554.15689
InChIKey
QUIJNHUBAXPXFS-XLJNKUFUSA-N
IUPAC Name
(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol
SMILES String
COc1nc2ccc(Br)cc2cc1[C@@H](c1ccccc1)[C@@](O)(CCN(C)C)c1cccc2ccccc12
Appearance
White solid
Melting Point
118.0 °C
XLogP
7.2
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Heavy atom count
37
H-bond acceptors
4
H-bond donors
1
Rotatable bonds
8
Ring count
5
Aromatic rings
5
Topological polar surface area
45.59 Ų
Computed LogP
7.13
Structural features
Bedaquiline (CAS 843663-66-1) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C32H31BrN2O2 and molecular weight 555. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
SDS signal word: Danger; hazard codes: H301, H373, H410; For research use only.
ChEMBL reports experimental activity evidence for: Putative uncharacterized protein atpE (Mycolicibacterium smegmatis) — 3 assays; Voltage-gated inwardly rectifying potassium channel KCNH2 (Homo sapiens) — 13 assays; Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 2 assays; Sodium-dependent dopamine transporter (Homo sapiens) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 5 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Catalog navigation
Linked by recorded structural or research relationships, not interchangeable products. Check the exact CAS, specification and availability on the linked product page.
Procurement notes
MolGraph uses public price and availability evidence as a starting point, then confirms current stock, quotation, COA/SDS, lot specification, lead time, and shipment documentation before final acceptance.
Use the quote panel for visible public options. Additional quantities or specifications can be reviewed by RFQ.
Purity, lot identity, and batch-specific documentation are confirmed before procurement decisions.
Supplier-issued COA and SDS can be requested before handling, storage, shipment, or procurement decisions.
Final quote depends on quantity, lead time, destination, and supplier confirmation.
Bedaquiline is listed as in-stock / available for research-use sourcing review. Final availability, lot specification, and lead time are confirmed by RFQ.
The page shows a public reference price in the quote panel. Submit an RFQ to confirm current price, quantity breaks, lead time, and destination-specific shipping requirements.
Yes. Supplier-issued COA and SDS can be requested during the RFQ workflow. Lot-specific documents depend on supplier and batch confirmation.
Fragment-like structure rule
No
Lead-like structure rule
No
Drug-like structure rule
No
Structure family
n heterocycle ligand
Precious metal motif
No
Transition metal motif
No
Phosphine ligand motif
No
N-heterocycle motif
Yes
Boronic acid motif
No
Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.
Putative uncharacterized protein atpE
Mycolicibacterium smegmatis · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 8.6
Experimental evidence source: ChEMBL
Voltage-gated inwardly rectifying potassium channel KCNH2
Homo sapiens · SINGLE PROTEIN · 13 qualifying assays · 12 documents · best pChEMBL 6.43
Experimental evidence source: ChEMBL
Replicase polyprotein 1ab
Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.36
Experimental evidence source: ChEMBL
Sodium-dependent dopamine transporter
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.54
Experimental evidence source: ChEMBL
Cytochrome P450 3A4
Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents
Experimental evidence source: ChEMBL
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS RequestSignal word: Danger
Supplier SDS reference cue; confirm supplier documentation before use.
Hazard statements: H301, H373, H410
Supplier SDS hazard code reference; confirm full text in supplier documentation.
Precautionary statements: P260, P264, P270, P273, P301+P310+P330, P314, P405, P501
Supplier SDS precautionary code reference; confirm full text in supplier documentation.
Shipment review: Required
Certificate of Analysis (COA): By request
Supplier Safety Data Sheet (SDS): By request
Purity and pack size confirmation: By request
Availability and lead time review: Confirmed by RFQ
Shipment documentation review: By request
For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference
Additional text reference cues are not available for this catalog entry.
Non-public references are shown as text only and do not imply equivalence, availability, or shared use.