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Home/Compounds/CAS 84573-16-0
Formula C29H31NO7MW 505.6Research-use catalog entryCOA/SDS by request

Rocaglamide

CAS Number: 84573-16-0

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Purity
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Loading RDKit molecule structure...
InChIKey: DAPAQENNNINUPW-IDAMAFBJSA-NC29H31NO7 | MW 505.6

Chemical Absolute Identifiers

CAS Number

84573-16-0

PubChem CID

331783

Molecular Formula

C29H31NO7

Molecular Weight

505.6 g/mol

Exact Mass

505.210052

InChIKey

DAPAQENNNINUPW-IDAMAFBJSA-N

IUPAC Name

(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide

SMILES String

CN(C)C(=O)[C@@H]1[C@H]([C@]2([C@@]([C@@H]1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Rocaglamide (CAS 84573-16-0) is listed in the Life Science portfolio, with molecular formula C29H31NO7 and molecular weight 505. 60 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Eukaryotic initiation factor 4A-I (Homo sapiens) — 6 assays; Transcription factor p65 (Homo sapiens) — 7 assays; Nuclear factor NF-kappa-B p105 subunit (Homo sapiens) — 3 assays; Geminin (Homo sapiens) — 2 assays; Nuclear factor erythroid 2-related factor 2 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Eukaryotic initiation factor 4A-I

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 2 documents · best pChEMBL 9

Experimental evidence source: ChEMBL

Transcription factor p65

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 7 documents · best pChEMBL 7.16

Experimental evidence source: ChEMBL

Nuclear factor NF-kappa-B p105 subunit

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.12

Experimental evidence source: ChEMBL

Geminin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Nuclear factor erythroid 2-related factor 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • The product Remaining and non-recyclable solutions should be handed over to a licensed company for disposal.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Rocaglamide

Names & Synonyms

Rocaglamide A1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan-2-carboxamide(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3,3a,8b-tetrahydro-1H-benzo(b)cyclopenta(d)furan-2-carboxamide(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta(b)(1)benzofuran-2-carboxamide
Show all synonyms
1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta(b)benzofuran-2-carboxamideRoc-A(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxamide(-)-(1alpha,2alpha,3beta,3abeta,8bbeta)-2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta(b)benzofuran-2-carboxamide(1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide(-)-ROCAGLAMIDEs7428(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b]benzofuran-2-carboxamide1H-Cyclopenta[b]benzofuran-2-carboxamide,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy- 3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-,(1R,2R,3S,3aR,8bS)-RCG
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID101004852CHEMBL ID: CHEMBL438139CHEBI ID: CHEBI:66309UNII: FRG4N852F7DRUGBANK ID: DB15495METABOLOMICS WORKBENCH ID: 64510WIKIDATA ID: Q3437403
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c01909Structural Chemistry of Helicase Inhibition.PMID 39933052Structural Chemistry of Helicase Inhibition.DOI 10.1021/acs.jmedchem.3c01357Halogenated Rocaglate Derivatives: Pan-antiviral Agents against Hepatitis E Virus and Emerging Viruses.PMID 38127656Halogenated Rocaglate Derivatives: Pan-antiviral Agents against Hepatitis E Virus and Emerging Viruses.DOI 10.1021/acs.jmedchem.0c01746Inhibitors of Eukaryotic Translational Machinery as Therapeutic Agents.PMID 33592144Inhibitors of Eukaryotic Translational Machinery as Therapeutic Agents.DOI 10.1016/j.ejmech.2020.112653Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses.DOI 10.1021/acs.jmedchem.0c00182Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

MosloflavoneCAS 740-33-0
TrismethoxyresveratrolCAS 22255-22-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 26049-94-5(3S)-3-Benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanoneCAS 6147-11-1MangostinCAS 508-02-1Oleanolic AcidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 84573-16-0

What are the key identifiers for Rocaglamide (CAS 84573-16-0)?

Rocaglamide is identified by CAS 84573-16-0, with molecular formula C29H31NO7, molecular weight 505.6, InChIKey DAPAQENNNINUPW-IDAMAFBJSA-N.

Does CAS 84573-16-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Eukaryotic initiation factor 4A-I, Transcription factor p65, Nuclear factor NF-kappa-B p105 subunit, Geminin, Nuclear factor erythroid 2-related factor 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 84573-16-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Rocaglamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 84573-16-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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