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Home/Compounds/CAS 86386-73-4
Formula C13H12F2N6OMW 306.27Research-use catalog entryCOA/SDS by request

Fluconazole

CAS Number: 86386-73-4

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Loading RDKit molecule structure...
InChIKey: RFHAOTPXVQNOHP-UHFFFAOYSA-NC13H12F2N6O | MW 306.27

Chemical Absolute Identifiers

CAS Number

86386-73-4

PubChem CID

3365

Molecular Formula

C13H12F2N6O

Molecular Weight

306.27 g/mol

Exact Mass

306.104065

InChIKey

RFHAOTPXVQNOHP-UHFFFAOYSA-N

IUPAC Name

2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol

SMILES String

C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O

Physical Properties

Melting Point

138–14 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Fluconazole (CAS 86386-73-4) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C13H12F2N6O and molecular weight 306. 27 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Sterol 14alpha-demethylase (Mycobacterium tuberculosis) — 3 assays; Cytochrome P450 3A4 (Homo sapiens) — 3 assays; Lanosterol 14-alpha demethylase (Homo sapiens) — 5 assays; Eukaryotic peptide chain release factor GTP-binding subunit (Saccharomyces cerevisiae) — 2 assays; Solute carrier organic anion transporter family member 1B1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Sterol 14alpha-demethylase

Mycobacterium tuberculosis · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 6.7

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 4.6

Experimental evidence source: ChEMBL

Lanosterol 14-alpha demethylase

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 4 documents · best pChEMBL 4.4

Experimental evidence source: ChEMBL

Eukaryotic peptide chain release factor GTP-binding subunit

Saccharomyces cerevisiae · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Solute carrier organic anion transporter family member 1B1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Fluconazole

Names & Synonyms

DiflucanTriflucanBiozoleneElazorFluconazol
Show all synonyms
ZoltecFlucostatdifluconazoleFluconazolumFlucazolFlunizolPritenzol2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-olUK 49858AlkanazoleFluconazoli1H-1,2,4-Triazole-1-ethanol, alpha-(2,4-difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-DIFLUCAN IN SODIUM CHLORIDE 0.9%
External Identifiers
EC NUMBER: 627-806-0EC NUMBER: 691-089-0DSSTOX SUBSTANCE ID: DTXSID3020627CHEMBL ID: CHEMBL106CHEBI ID: CHEBI:46081UNII: 8VZV102JFYDRUGBANK ID: DB00196HMDB ID: HMDB0014342KEGG ID: C07002KEGG ID: D00322METABOLOMICS WORKBENCH ID: 42604NCI THESAURUS CODE: C500PHARMGKB ID: PA449653RXCUI: 4450WIKIDATA ID: Q411478
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.bmc.2013.12.016Salicylanilide diethyl phosphates: synthesis, antimicrobial activity and cytotoxicity.DOI 10.1016/j.bmcl.2013.11.0131,2,3-Triazole-derived naphthalimides as a novel type of potential antimicrobial agents: synthesis, antimicrobial activity, interaction with calf thymus DNA and human serum albumin.DOI 10.1016/j.bmcl.2013.11.037Synthesis and evaluation of novel azoles as potent antifungal agents.DOI 10.1016/j.bmcl.2013.12.010Synthesis and antimicrobial activities of novel 1,2,4-triazolo [3,4-a] phthalazine derivatives.DOI 10.1016/j.bmcl.2014.01.022Antifungal ether diglycosides from Matayba guianensis Aublet.DOI 10.1016/j.bmcl.2014.01.035Synthesis, antileishmanial activity and docking study of N'-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetohydrazides.DOI 10.1016/j.bmcl.2014.02.005Activity of caffeic acid derivatives against Candida albicans biofilm.DOI 10.1016/j.ejmech.2012.09.047Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Fluconazole hydrateCAS 155347-36-7
Fluconazole (mesylate)CAS 159532-41-9
FosfluconazoleCAS 194798-83-9
VoriconazoleCAS 137234-62-9
EfinaconazoleCAS 164650-44-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 155347-36-7Fluconazole hydrateCAS 159532-41-9Fluconazole (mesylate)CAS 194798-83-9FosfluconazoleCAS 137234-62-9VoriconazoleCAS 164650-44-6EfinaconazoleCAS 65277-42-11-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanoneCAS 114-07-8ErythromycinCAS 13292-46-1RifampicinCAS 23593-75-1ClotrimazoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 86386-73-4

What are the key identifiers for Fluconazole (CAS 86386-73-4)?

Fluconazole is identified by CAS 86386-73-4, with molecular formula C13H12F2N6O, molecular weight 306.27, InChIKey RFHAOTPXVQNOHP-UHFFFAOYSA-N.

Does CAS 86386-73-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Sterol 14alpha-demethylase, Cytochrome P450 3A4, Lanosterol 14-alpha demethylase, Eukaryotic peptide chain release factor GTP-binding subunit, Solute carrier organic anion transporter family member 1B1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 86386-73-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Fluconazole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 86386-73-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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