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CAS Number: 871700-17-3
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CAS Number
871700-17-3
PubChem CID
11707110
Molecular Formula
C26H23FIN5O4
Molecular Weight
615.4 g/mol
Exact Mass
615.07788
InChIKey
LIRYPHYGHXZJBZ-UHFFFAOYSA-N
IUPAC Name
N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
SMILES String
CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)c1
Water Solubility
1 mol/L
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Trametinib (CAS 871700-17-3) is listed in the Advanced Chemicals portfolio, with molecular formula C26H23FIN5O4 and molecular weight 615. 40 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens) — 20 assays; Dual specificity mitogen-activated protein kinase kinase 2 (Homo sapiens) — 18 assays; Mitogen-activated protein kinase 1 (Homo sapiens) — 4 assays; Tyrosine-protein kinase ABL1 (Homo sapiens) — 4 assays; Aurora kinase A (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Dual specificity mitogen-activated protein kinase kinase 1
Homo sapiens · SINGLE PROTEIN · 20 qualifying assays · 8 documents · best pChEMBL 9.32
Experimental evidence source: ChEMBL
Dual specificity mitogen-activated protein kinase kinase 2
Homo sapiens · SINGLE PROTEIN · 18 qualifying assays · 7 documents · best pChEMBL 9.32
Experimental evidence source: ChEMBL
Mitogen-activated protein kinase 1
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents
Experimental evidence source: ChEMBL
Tyrosine-protein kinase ABL1
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents
Experimental evidence source: ChEMBL
Aurora kinase A
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
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Trametinib is identified by CAS 871700-17-3, with molecular formula C26H23FIN5O4, molecular weight 615.4, InChIKey LIRYPHYGHXZJBZ-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Dual specificity mitogen-activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, Mitogen-activated protein kinase 1, Tyrosine-protein kinase ABL1, Aurora kinase A. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
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