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Home/Compounds/CAS 89-57-6
Formula C7H7NO3MW 153.14Research-use catalog entryCOA/SDS by request

5-Aminosalicylic Acid

CAS Number: 89-57-6

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Loading RDKit molecule structure...
InChIKey: KBOPZPXVLCULAV-UHFFFAOYSA-NC7H7NO3 | MW 153.14

Chemical Absolute Identifiers

CAS Number

89-57-6

PubChem CID

4075

Molecular Formula

C7H7NO3

Molecular Weight

153.14 g/mol

Exact Mass

153.042593

InChIKey

KBOPZPXVLCULAV-UHFFFAOYSA-N

IUPAC Name

5-amino-2-hydroxybenzoic acid

SMILES String

C1=CC(=C(C=C1N)C(=O)O)O

Physical Properties

Appearance

5-aminosalicylic acid appears as odorless white to pinkish crystals or purplish-tan powder. Aqueous solutions acidic (pH approximately 4.1 at 0.8 mg/L water). (NTP, 1992)

Melting Point

283.0 °C

Show more physical data

Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

5-Aminosalicylic Acid (CAS 89-57-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C7H7NO3 and molecular weight 153. 14 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: GroEL/GroES (Escherichia coli) — 4 assays; Cytochrome P450 2C19 (Homo sapiens) — 2 assays; 2-Hydroxyacid oxidase 1 (Mus musculus) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 3 assays; 3-hydroxyacyl-CoA dehydrogenase type-2 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

GroEL/GroES

Escherichia coli · PROTEIN COMPLEX · 4 qualifying assays · 1 documents · best pChEMBL 6.31

Experimental evidence source: ChEMBL

Cytochrome P450 2C19

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.3

Experimental evidence source: ChEMBL

2-Hydroxyacid oxidase 1

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.11

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.1

Experimental evidence source: ChEMBL

3-hydroxyacyl-CoA dehydrogenase type-2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

5-Aminosalicylic Acid

Names & Synonyms

mesalamineMesalazine5-ASAFisalamineLialda
Show all synonyms
m-Aminosalicylic acidBenzoic acid, 5-amino-2-hydroxy-AprisoMesalazinasfRowasaAsacolitinMesalazinumIialdap-AminosalicylsaeureAsacol HDPentacol3-carboxy-4-hydroxyanilineDelzicolMezavant XL
External Identifiers
EC NUMBER: 201-919-1DSSTOX SUBSTANCE ID: DTXSID5024506CHEMBL ID: CHEMBL704CHEBI ID: CHEBI:6775UNII: 4Q81I59GXCDRUGBANK ID: DB00244HMDB ID: HMDB0014389KEGG ID: C07138KEGG ID: D00377METABOLOMICS WORKBENCH ID: 42646NCI THESAURUS CODE: C29249PHARMGKB ID: PA450384RXCUI: 52582WIKIDATA ID: Q412479
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Bio-Rad Laboratories
Literature & Patent References
DOI 10.1016/j.bmc.2025.118145Rational design, synthesis and anti-inflammatory activity of 6-substituted dihydrobenzophenanthridine derivatives.DOI 10.1021/acs.jmedchem.4c02774Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis.DOI 10.1021/acs.jmedchem.4c02883Development of Hydrazide-Based HDAC6 Selective Inhibitors for Treating NLRP3 Inflammasome-Related Diseases.PMID 40012371Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis.PMID 40056889Rational design, synthesis and anti-inflammatory activity of 6-substituted dihydrobenzophenanthridine derivatives.PMID 40193276Development of Hydrazide-Based HDAC6 Selective Inhibitors for Treating NLRP3 Inflammasome-Related Diseases.DOI 10.1016/j.ejmech.2024.116252Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice.DOI 10.1016/j.ejmech.2024.116426Design, synthesis, and biological evaluation of novel sesquiterpene lactone derivatives as PKM2 activators with potent anti-ulcerative colitis activities.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

5-Nitrosalicylic acidCAS 96-97-9
Salicylic AcidCAS 69-72-7
4-HydroxybenzamideCAS 619-57-8
3-Fluorophenylacetic acidCAS 331-25-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 96-97-95-Nitrosalicylic acidCAS 69-72-7Salicylic AcidCAS 21829-25-4NifedipineCAS 97-18-7BithionolCAS 114-07-8ErythromycinCAS 169590-42-5CelecoxibCAS 22204-53-1NaproxenCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 89-57-6

What are the key identifiers for 5-Aminosalicylic Acid (CAS 89-57-6)?

5-Aminosalicylic Acid is identified by CAS 89-57-6, with molecular formula C7H7NO3, molecular weight 153.14, InChIKey KBOPZPXVLCULAV-UHFFFAOYSA-N.

Does CAS 89-57-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with GroEL/GroES, Cytochrome P450 2C19, 2-Hydroxyacid oxidase 1, Cytochrome P450 3A4, 3-hydroxyacyl-CoA dehydrogenase type-2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 89-57-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 5-Aminosalicylic Acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 89-57-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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