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Home/Compounds/CAS 89786-04-9
Formula C10H12N4O5SMW 300.29Research-use catalog entryCOA/SDS by request

Tazobactam

CAS Number: 89786-04-9

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Loading RDKit molecule structure...
InChIKey: LPQZKKCYTLCDGQ-WEDXCCLWSA-NC10H12N4O5S | MW 300.29

Chemical Absolute Identifiers

CAS Number

89786-04-9

PubChem CID

123630

Molecular Formula

C10H12N4O5S

Molecular Weight

300.29 g/mol

Exact Mass

300.052841

InChIKey

LPQZKKCYTLCDGQ-WEDXCCLWSA-N

IUPAC Name

(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

SMILES String

C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3

Physical Properties

pKa

2.1

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Tazobactam (CAS 89786-04-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C10H12N4O5S and molecular weight 300. 29 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Beta-lactamase TEM (Escherichia coli) — 9 assays; Beta-lactamase TEM (Bacteria) — 2 assays; IMI-1 (Enterobacter cloacae) — 2 assays; Beta-lactamase (Enterobacter cloacae) — 21 assays; Beta-lactamase SHV-1 (Escherichia coli) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Beta-lactamase TEM

Escherichia coli · SINGLE PROTEIN · 9 qualifying assays · 8 documents · best pChEMBL 7.77

Experimental evidence source: ChEMBL

Beta-lactamase TEM

Bacteria · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.76

Experimental evidence source: ChEMBL

IMI-1

Enterobacter cloacae · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.52

Experimental evidence source: ChEMBL

Beta-lactamase

Enterobacter cloacae · SINGLE PROTEIN · 21 qualifying assays · 8 documents · best pChEMBL 7

Experimental evidence source: ChEMBL

Beta-lactamase SHV-1

Escherichia coli · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 6.65

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Tazobactam

Names & Synonyms

TazobactamumCL 298,741(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 4,4-dioxide4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4$l^(6)-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
Show all synonyms
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-Tazobactam acidYTR 830H(2S,3S,5R)-3-METHYL-4,4,7-TRIOXO-3-(1H-1,2,3-TRIAZOL-1-YLMETHYL)-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID(2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxideYTR 830(2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxideYTR 830 H(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxideTazobactamum [INN-Latin]CCRIS 2203Tazobactam [USAN:USP:INN:BAN]89786-04-9 (free acid)
External Identifiers
EC NUMBER: 618-303-7DSSTOX SUBSTANCE ID: DTXSID8023634CHEMBL ID: CHEMBL404CHEBI ID: CHEBI:9421UNII: SE10G96M8WDRUGBANK ID: DB01606HMDB ID: HMDB0015544KEGG ID: C07771KEGG ID: D00660METABOLOMICS WORKBENCH ID: 43592NCI THESAURUS CODE: C62079PHARMGKB ID: PA164764504RXCUI: 37617WIKIDATA ID: Q423376
Literature & Patent References
DOI 10.1016/j.ejmech.2025.117479Cross-subclass metallo-β-lactamase inhibitors: From structural and catalytic commonalities guiding design.PMID 40056799Cross-subclass metallo-β-lactamase inhibitors: From structural and catalytic commonalities guiding design.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1021/acs.jmedchem.1c003696-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of <i>Pseudomonas aeruginosa</i> to β-Lactam Antibiotics.DOI 10.1021/acs.jmedchem.1c00790Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
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  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

SulbactamCAS 68373-14-8
potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylateCAS 113-98-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 68373-14-8SulbactamCAS 61477-96-1PiperacillinCAS 209467-52-7CeftobiproleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 89786-04-9

What are the key identifiers for Tazobactam (CAS 89786-04-9)?

Tazobactam is identified by CAS 89786-04-9, with molecular formula C10H12N4O5S, molecular weight 300.29, InChIKey LPQZKKCYTLCDGQ-WEDXCCLWSA-N.

Does CAS 89786-04-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Beta-lactamase TEM, Beta-lactamase TEM, IMI-1, Beta-lactamase, Beta-lactamase SHV-1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 89786-04-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Tazobactam?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 89786-04-9 available for quotation?

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