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Home/Compounds/CAS 920035-77-4
Formula C20H13Cl2N5O2MW 426.3Research-use catalog entryCOA/SDS by request

MK-4965

CAS Number: 920035-77-4

Sourcing & RFQ

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Available options

Available Options

Package
100 mg
Purity
98+%
Price
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Availability
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Loading RDKit molecule structure...
InChIKey: KXDIHAQCVNNLIB-UHFFFAOYSA-NC20H13Cl2N5O2 | MW 426.3

Chemical Absolute Identifiers

CAS Number

920035-77-4

PubChem CID

16045418

Molecular Formula

C20H13Cl2N5O2

Molecular Weight

426.3 g/mol

Exact Mass

425.04463

InChIKey

KXDIHAQCVNNLIB-UHFFFAOYSA-N

IUPAC Name

3-[5-[(6-amino-2H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chlorophenoxy]-5-chlorobenzonitrile

SMILES String

C1=CC(=C(C=C1OCC2=C3C=CC(=NC3=NN2)N)OC4=CC(=CC(=C4)C#N)Cl)Cl

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

MK-4965 (CAS 920035-77-4) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C20H13Cl2N5O2 and molecular weight 426. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) — 14 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Human immunodeficiency virus type 1 reverse transcriptase

Human immunodeficiency virus 1 · SINGLE PROTEIN · 14 qualifying assays · 6 documents · best pChEMBL 9.7

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

MK-4965

Names & Synonyms

3-(5-((6-Amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy)-2-chlorophenoxy)-5-chlorobenzonitrile3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrileBenzonitrile, 3-(5-((6-amino-1H-pyrazolo(3,4-b)pyridin-3-yl)methoxy)-2-chlorophenoxy)-5-chloro-Benzonitrile, 3-[5-[(6-amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chlorophenoxy]-5-chloro-3-(5-((6-amino-1H-pyrazolo(3,4-b)pyridin-3-yl)methoxy)-2-chlorophenoxy)-5-chlorobenzonitrile
Show all synonyms
MK 49653drp3drrR8E3-(5-((6-amino-1h-pyrazolo(3,4-b)pyridine-3-yl)methoxy)-2-chlorophenoxy)-5-chlorobenzonitrile3-[5-[(6-amino-1H-pyrazolo[3,4-b]pyridin-3-yl)methoxy]-2-chloro-phenoxy]-5-chloro-benzonitrile
External Identifiers
CHEMBL ID: CHEMBL489586UNII: Z8856WDK9SDRUGBANK ID: DB08460METABOLOMICS WORKBENCH ID: 151593WIKIDATA ID: Q27097666
Literature & Patent References
DOI 10.1021/ml300146qDiscovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.PMID 24900529Discovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.DOI 10.1016/j.bmcl.2011.10.027Design and synthesis of pyridone inhibitors of non-nucleoside reverse transcriptase.DOI 10.1021/jm2010173Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.PMID 21985673Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.PMID 22071300Design and synthesis of pyridone inhibitors of non-nucleoside reverse transcriptase.DOI 10.1021/jm901230rBiaryl ethers as novel non-nucleoside reverse transcriptase inhibitors with improved potency against key mutant viruses.DOI 10.1128/aac.01559-08Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

DoravirineCAS 1338225-97-0
EtravirineCAS 269055-15-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 920035-77-4

What are the key identifiers for MK-4965 (CAS 920035-77-4)?

MK-4965 is identified by CAS 920035-77-4, with molecular formula C20H13Cl2N5O2, molecular weight 426.3, InChIKey KXDIHAQCVNNLIB-UHFFFAOYSA-N.

Does CAS 920035-77-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Human immunodeficiency virus type 1 reverse transcriptase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 920035-77-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for MK-4965?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 920035-77-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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