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Home/Compounds/CAS 925206-65-1
Formula C5H6BrN3O5MW 268.02Research-use catalog entryCOA/SDS by request

Rrx-001

CAS Number: 925206-65-1

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Loading RDKit molecule structure...
InChIKey: JODKFOVZURLVTG-UHFFFAOYSA-NC5H6BrN3O5 | MW 268.02

Chemical Absolute Identifiers

CAS Number

925206-65-1

PubChem CID

15950826

Molecular Formula

C5H6BrN3O5

Molecular Weight

268.02 g/mol

Exact Mass

266.94908

InChIKey

JODKFOVZURLVTG-UHFFFAOYSA-N

IUPAC Name

2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone

SMILES String

O=C(CBr)N1CC([N+](=O)[O-])([N+](=O)[O-])C1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Rrx-001 (CAS 925206-65-1) is listed in the Advanced Chemicals portfolio, with molecular formula C5H6BrN3O5 and molecular weight 268. 02 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Rrx-001

Names & Synonyms

2-BROMO-1-(3,3-DINITROAZETIDIN-1-YL)ETHAN-1-ONENibrozetoneABDNAZRadiosensitizer rrx-001Rrx 001
Show all synonyms
Ethanone, 2-bromo-1-(3,3-dinitro-1-azetidinyl)-C5H6BrN3O5Nibrozetone (USAN)NIBROZETONE [USAN]RRx001Nibrozetonanibrozetone [INN]RRX 001 [WHO-DD]RRx-001?1-bromoacetyl-3,3-dinitroazetidines8405n-(bromoacetyl)-3,3-dinitroazetidine2-Bromo-1-(3,3-dinitro-1-azetidinyl)ethanone
External Identifiers
CHEMBL ID: CHEMBL3526802UNII: 7RPW6SU9SCDRUGBANK ID: DB12060KEGG ID: D12720METABOLOMICS WORKBENCH ID: 153116NCI THESAURUS CODE: C97130WIKIDATA ID: Q27268765
Literature & Patent References
DOI 10.1016/j.ejmech.2021.114053A review on the treatment of multiple myeloma with small molecular agents in the past five years.PMID 34974338A review on the treatment of multiple myeloma with small molecular agents in the past five years.DOI 10.1021/acs.jmedchem.1c00599Discovery of RRx-001, a Myc and CD47 Downregulating Small Molecule with Tumor Targeted Cytotoxicity and Healthy Tissue Cytoprotective Properties in Clinical Development.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 34043360Discovery of RRx-001, a Myc and CD47 Downregulating Small Molecule with Tumor Targeted Cytotoxicity and Healthy Tissue Cytoprotective Properties in Clinical Development.DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

2-Bromo-1-(3-fluoro-3-methyl-azetidin-1-yl)ethanoneCAS 1466514-89-5
N-BromoacetylazetidineCAS 885267-00-5
Tert-butyl 3-hydroxy-3-(nitromethyl)azetidine-1-carboxylateCAS 1008526-70-2
1-Boc-3-fluoroazetidine-3-methanolCAS 1126650-66-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1466514-89-52-Bromo-1-(3-fluoro-3-methyl-azetidin-1-yl)ethanoneCAS 885267-00-5N-BromoacetylazetidineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 925206-65-1

What are the key identifiers for Rrx-001 (CAS 925206-65-1)?

Rrx-001 is identified by CAS 925206-65-1, with molecular formula C5H6BrN3O5, molecular weight 268.02, InChIKey JODKFOVZURLVTG-UHFFFAOYSA-N.

Does CAS 925206-65-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 925206-65-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Rrx-001?

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Is CAS 925206-65-1 available for quotation?

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