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Home/Compounds/CAS 938440-64-3
Formula C25H31N5O4MW 465.5Research-use catalog entryCOA/SDS by request

Ku-0063794

CAS Number: 938440-64-3

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Loading RDKit molecule structure...
InChIKey: RFSMUFRPPYDYRD-CALCHBBNSA-NC25H31N5O4 | MW 465.5

Chemical Absolute Identifiers

CAS Number

938440-64-3

PubChem CID

16736978

Molecular Formula

C25H31N5O4

Molecular Weight

465.5 g/mol

Exact Mass

465.237604

InChIKey

RFSMUFRPPYDYRD-CALCHBBNSA-N

IUPAC Name

[5-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol

SMILES String

COc1ccc(-c2ccc3c(N4CCOCC4)nc(N4C[C@@H](C)O[C@@H](C)C4)nc3n2)cc1CO

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ku-0063794 (CAS 938440-64-3) is listed in the Advanced Chemicals portfolio, with molecular formula C25H31N5O4 and molecular weight 465. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Serine/threonine-protein kinase mTOR (Homo sapiens) — 6 assays; mTORC1 (Homo sapiens) — 13 assays; mTORC2 (Homo sapiens) — 5 assays; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens) — 2 assays; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Serine/threonine-protein kinase mTOR

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 8.6

Experimental evidence source: ChEMBL

mTORC1

Homo sapiens · PROTEIN COMPLEX · 13 qualifying assays · 5 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

mTORC2

Homo sapiens · PROTEIN COMPLEX · 5 qualifying assays · 3 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.28

Experimental evidence source: ChEMBL

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 5.05

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Ku-0063794

Names & Synonyms

KU 0063794Ku 63794(5-{2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-(morpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanolrel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanolBenzenemethanol, 5-(2-((2R,6S)-2,6-dimethyl-4-morpholinyl)-4-(4-morpholinyl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxy-
Show all synonyms
[5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[5,6-e]pyrimidin-7-yl]-2-methoxyphenyl]methanol(5-(2-((2R,6S)-2,6-dimethylmorpholin-4-yl)-4-(morpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol(5-(2-((2R,6S)-2,6-dimethylmorpholin-4-yl)-4-morpholin-4-ylpyrido(5,6-e)pyrimidin-7-yl)-2-methoxyphenyl)methanolrel-5-(2-((2R,6S)-2,6-Dimethyl-4-morpholinyl)-4-(4-morpholinyl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxybenzenemethanol(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol(5-(2-(cis-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol[5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanolrel-5-[2-[(2R,6S)-2,6-dimethyl-4-mo rpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin -7-yl]-2-methoxybenzenemethanol[5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholino-pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-phenyl]methanols1226SDCCGSBI-0654360.P0015-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenKU 0063794, >=98% (HPLC){5-[2-((2S,6R)-2,6-Dimethyl-morpholin-4-yl)-4-morpholin-4-yl-pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-phenyl}-methanol
External Identifiers
EC NUMBER: 804-413-4DSSTOX SUBSTANCE ID: DTXSID50239782CHEMBL ID: CHEMBL1078983CHEBI ID: CHEBI:85572UNII: 81HJG228ABWIKIDATA ID: Q27158643Ku63794
Literature & Patent References
DOI 10.1016/j.bmc.2023.117561Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.DOI 10.1016/j.ejmech.2023.116117Targeting autophagy drug discovery: Targets, indications and development trends.DOI 10.1016/j.ejmech.2024.116688Autophagy modulation in cancer therapy: Challenges coexist with opportunities.PMID 38157838Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.PMID 38295689Targeting autophagy drug discovery: Targets, indications and development trends.PMID 39033611Autophagy modulation in cancer therapy: Challenges coexist with opportunities.DOI 10.1016/j.bmcl.2021.128204Design, synthesis and biological evaluation of dual mTOR/HDAC6 inhibitors in MDA-MB-231 cells.DOI 10.6019/CHEMBL4689842EUbOPEN Chemogenomics Library wave 1

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

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Text Reference Cues

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Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 120685-11-2MidostaurinCAS 571190-30-2PalbociclibCAS 62996-74-1StaurosporineCAS 1009298-09-2Azd8055CAS 1262888-28-7Spautin-1CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 938440-64-3

What are the key identifiers for Ku-0063794 (CAS 938440-64-3)?

Ku-0063794 is identified by CAS 938440-64-3, with molecular formula C25H31N5O4, molecular weight 465.5, InChIKey RFSMUFRPPYDYRD-CALCHBBNSA-N.

Does CAS 938440-64-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Serine/threonine-protein kinase mTOR, mTORC1, mTORC2, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 938440-64-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ku-0063794?

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Is CAS 938440-64-3 available for quotation?

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