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Home/Compounds/CAS 97-18-7
Formula C12H6Cl4O2SMW 356Research-use catalog entryCOA/SDS by request

Bithionol

CAS Number: 97-18-7

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98%
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Loading RDKit molecule structure...
InChIKey: JFIOVJDNOJYLKP-UHFFFAOYSA-NC12H6Cl4O2S | MW 356

Chemical Absolute Identifiers

CAS Number

97-18-7

PubChem CID

2406

Molecular Formula

C12H6Cl4O2S

Molecular Weight

356 g/mol

Exact Mass

355.881311

InChIKey

JFIOVJDNOJYLKP-UHFFFAOYSA-N

IUPAC Name

2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfanylphenol

SMILES String

C1=C(C=C(C(=C1SC2=C(C(=CC(=C2)Cl)Cl)O)O)Cl)Cl

Physical Properties

Appearance

2,2'-thiobis(4,6-dichlorophenol) appears as white or grayish white crystalline powder with a very faint aromatic or phenolic odor. (NTP, 1992)

Melting Point

185.5–188 °C

Density

1.73 g/cm³

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Bithionol (CAS 97-18-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C12H6Cl4O2S and molecular weight 356. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Transthyretin (Homo sapiens) — 9 assays; Mitogen-activated protein kinase 1 (Homo sapiens) — 2 assays; Adenosine receptor A3 (Homo sapiens) — 2 assays; Nuclear receptor subfamily 1 group I member 2 (Homo sapiens) — 4 assays; Sodium-dependent noradrenaline transporter (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Transthyretin

Homo sapiens · SINGLE PROTEIN · 9 qualifying assays · 1 documents · best pChEMBL 7.21

Experimental evidence source: ChEMBL

Mitogen-activated protein kinase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.42

Experimental evidence source: ChEMBL

Adenosine receptor A3

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.33

Experimental evidence source: ChEMBL

Nuclear receptor subfamily 1 group I member 2

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 6

Experimental evidence source: ChEMBL

Sodium-dependent noradrenaline transporter

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.91

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Bithionol

Names & Synonyms

BithinLorothidolActamer2,2'-Thiobis(4,6-dichlorophenol)Bitionol
Show all synonyms
BidiphenBisoxyphenLorothiodolBithionol sulfideBithionolateNeopellisBitinVancide BLTKhsd2-Hydroxy-3,5-dichlorophenyl sulfideBithionolumBis(2-hydroxy-3,5-dichlorophenyl) sulfideBis(3,5-dichloro-2-hydroxyphenyl) sulfide2,2'-sulfanediylbis(4,6-dichlorophenol)2-Hydroxy-3,5-dichlorophenyl sulphide
External Identifiers
EC NUMBER: 202-565-0DSSTOX SUBSTANCE ID: DTXSID9021342CHEMBL ID: CHEMBL290106CHEBI ID: CHEBI:3131UNII: AMT77LS62ODRUGBANK ID: DB04813HMDB ID: HMDB0249278KEGG ID: C07967KEGG ID: D00802METABOLOMICS WORKBENCH ID: 53014NCI THESAURUS CODE: C77030WIKIDATA ID: Q4918862
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraUV-VIS Spectra
Literature & Patent References
DOI 10.1021/acsmedchemlett.5c00061From Natural Products to Small Molecules: Recent Advancements in Anti-MRSA Therapeutics.PMID 40236547From Natural Products to Small Molecules: Recent Advancements in Anti-MRSA Therapeutics.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/EOS300108ECBD screening data for assay EOS300108PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1016/j.ejmech.2022.114550Membrane acting Povarov-Doebner derived compounds potently disperse preformed multidrug resistant Gram-positive bacterial biofilms.DOI 10.1021/acs.jmedchem.2c00289Discovery and Mechanistic Study of <i>Mycobacterium tuberculosis</i> PafA Inhibitors.PMID 35793578Membrane acting Povarov-Doebner derived compounds potently disperse preformed multidrug resistant Gram-positive bacterial biofilms.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Bithionol sulfoxideCAS 844-26-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 844-26-8Bithionol sulfoxideCAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 302-79-4Retinoic AcidCAS 139481-59-7CandesartanCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 97-18-7

What are the key identifiers for Bithionol (CAS 97-18-7)?

Bithionol is identified by CAS 97-18-7, with molecular formula C12H6Cl4O2S, molecular weight 356, InChIKey JFIOVJDNOJYLKP-UHFFFAOYSA-N.

Does CAS 97-18-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Transthyretin, Mitogen-activated protein kinase 1, Adenosine receptor A3, Nuclear receptor subfamily 1 group I member 2, Sodium-dependent noradrenaline transporter. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 97-18-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Bithionol?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 97-18-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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