5-(Cyclopropyl)-2-trifluoromethylpyridine-4-boronic acid

5-(Cyclopropyl)-2-trifluoromethylpyridine-4-boronic acid, with CAS 2225175-30-2, is a highly functionalized pyridine boronic acid. Its structure incorporates a pyridine ring substituted with a cyclopropyl group at position 5, a trifluoromethyl group at position 2, and a boronic acid moiety at position 4. This compound is primarily utilized as a key intermediate in various synthetic routes, especially in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling, to construct complex organic molecules. Its trifluoromethyl and cyclopropyl groups can introduce specific electronic and steric properties, making it valuable for developing novel compounds in research and development settings.

• Handle 5-(Cyclopropyl)-2-trifluoromethylpyridine-4-boronic acid with appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Prevent skin and eye contact, and do not ingest. Store in a cool, dry place, away from incompatible materials. Dispose of waste according to local regulations for chemical waste.