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2-Chloro-5-(trifluoromethyl)pyridine-4-boronic acid pinacol ester

CAS 2121515-21-5Formula C12H14BClF3NO2MW 307.5PubChem 74789416

2-Chloro-5-(trifluoromethyl)pyridine-4-boronic acid pinacol ester is a functionalized pyridine derivative used as a versatile building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to construct complex pyridine-containing structures. It is intended for Research Use Only (RUO).

Loading RDKit molecule structure...
InChIKey: RSFBRSNYUZUDAM-UHFFFAOYSA-NC12H14BClF3NO2 | MW 307.5

Chemical Identity

Molecular Formula

C12H14BClF3NO2

Molecular Weight

307.5 g/mol

Exact Mass

307.075821

PubChem CID

74789416

IUPAC Name

2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine

SMILES String

CC1(C)OB(c2cc(Cl)ncc2C(F)(F)F)OC1(C)C

Names & Synonyms

881-598-82-chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridineE91667
External Identifiers
RefChem:469274MFCD18738555SY316015CS-0177330

Catalog Overview

2-Chloro-5-(trifluoromethyl)pyridine-4-boronic acid pinacol ester (CAS 2121515-21-5) is a functionalized pyridine derivative featuring a chloro group, a trifluoromethyl group, and a pinacol boronic ester moiety. This compound serves as a versatile building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The presence of the chloro and trifluoromethyl groups allows for further chemical modifications or introduces specific electronic and steric properties, making it valuable in the synthesis of complex organic molecules, including potential...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

2-Chloro-5-(trifluoromethyl)pyridine-4-boronic acid pinacol ester (CAS 2121515-21-5) is a functionalized pyridine derivative featuring a chloro group, a trifluoromethyl group, and a pinacol boronic ester moiety. This compound serves as a versatile building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The presence of the chloro and trifluoromethyl groups allows for further chemical modifications or introduces specific electronic and steric properties, making it valuable in the synthesis of complex organic molecules, including potential pharmaceutical intermediates and agrochemicals. This product is intended for Research Use Only (RUO).

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white crystalline powder

Physical State

Solid

Melting Point

137.0 °C

Boiling Point

264.0 °C

Density

1.4 g/cm³

Water Solubility

4.07 × 10⁻⁴ mol/L

Flash Point

157.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation of dust or vapors. Prevent ingestion and skin contact. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety information before use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293499GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.