1-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carbonitrile

1-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carbonitrile is a complex organic compound characterized by a cyclopropane ring substituted with a nitrile group, a fluorinated phenyl moiety, and a pinacol boronic ester. This trifunctional structure makes it a valuable intermediate in the synthesis of diverse organic molecules, particularly in pharmaceutical and agrochemical research. The boronic ester group is highly reactive in cross-coupling reactions, such as Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The fluorine atom and cyclopropane-carbonitrile group introduce specific steric and electronic properties that can be advantageous in drug discovery and material science applications.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Do not ingest. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.