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Home/Compounds/CAS 1132709-14-8
Formula C19H25BN4O4MW 384.2Research-use catalog entryCOA/SDS by request

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

CAS Number: 1132709-14-8

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Loading RDKit molecule structure...
InChIKey: GXJABQQUPOEUTA-DOTOQJQBSA-NC19H25BN4O4 | MW 384.2

Chemical Absolute Identifiers

CAS Number

1132709-14-8

PubChem CID

24871309

Molecular Formula

C19H25BN4O4

Molecular Weight

384.2 g/mol

Exact Mass

384.196886

InChIKey

GXJABQQUPOEUTA-DOTOQJQBSA-N

IUPAC Name

[(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid

SMILES String

CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid (CAS 1132709-14-8) is listed in the Advanced Chemicals portfolio, with molecular formula C19H25BN4O4 and molecular weight 384. 20 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle, boronic-acid-related structure.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Boronic Acids and EstersSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor ROR-gamma (Mus musculus) — 2 assays; Peripheral myelin protein 22 (Rattus norvegicus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor ROR-gamma

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.1

Experimental evidence source: ChEMBL

Peripheral myelin protein 22

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

Names & Synonyms

(1S,2S)-Bortezomib[(1S)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid[(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazin-2-ylcarbonylamino)propanoyl]amino]butyl]boronic acidBortezomib 10mgBortezomib, (1S,2S)-
Show all synonyms
cid_24871309N-[(1S)-1-Borono-3-methylbutyl]-Nalpha-(pyrazine-2-carbonyl)-L-phenylalaninamideB-[(1S)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acidBoronic acid, B-[(1S)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID30647765CHEMBL ID: CHEMBL524664UNII: PQ2SUA6Q7GWIKIDATA ID: Q82560345
Literature & Patent References
DOI 10.1021/acs.jmedchem.0c02152Structure-Based Design of Selective LONP1 Inhibitors for Probing <i>In Vitro</i> Biology.PMID 33821636Structure-Based Design of Selective LONP1 Inhibitors for Probing <i>In Vitro</i> Biology.DOI 10.1016/j.bmc.2012.11.045Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein.PMID 23294826Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein.DOI 10.1021/jm9005093Design, synthesis, biological evaluation, and structure-activity relationship (SAR) discussion of dipeptidyl boronate proteasome inhibitors, part I: comprehensive understanding of the SAR of alpha-amino acid boronates.PMID 19537716Design, synthesis, biological evaluation, and structure-activity relationship (SAR) discussion of dipeptidyl boronate proteasome inhibitors, part I: comprehensive understanding of the SAR of alpha-amino acid boronates.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

B-((1R)-3-Methyl-1-(((2R)-1-oxo-3-phenyl-2-((2-pyrazinylcarbonyl)amino)propyl)amino)butyl)boronic acidCAS 1132709-15-9
Bortezomib boronic anhydrideCAS 390800-88-1
DelanzomibCAS 847499-27-8
IxazomibCAS 1072833-77-2
(2-(((Benzyloxy)carbonyl)amino)ethyl)boronic acidCAS 4540-87-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1132709-15-9B-((1R)-3-Methyl-1-(((2R)-1-oxo-3-phenyl-2-((2-pyrazinylcarbonyl)amino)propyl)amino)butyl)boronic acidCAS 390800-88-1Bortezomib boronic anhydrideCAS 847499-27-8DelanzomibCAS 119413-54-6Topotecan HydrochlorideCAS 120068-37-3FipronilCAS 1239-45-8Ethidium BromideCAS 179324-69-7BortezomibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1132709-14-8

What are the key identifiers for ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid (CAS 1132709-14-8)?

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid is identified by CAS 1132709-14-8, with molecular formula C19H25BN4O4, molecular weight 384.2, InChIKey GXJABQQUPOEUTA-DOTOQJQBSA-N.

Does CAS 1132709-14-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor ROR-gamma, Peripheral myelin protein 22. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1132709-14-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

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