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Home/Compounds/CAS 847499-27-8
Formula C21H28BN3O5MW 413.3Research-use catalog entryCOA/SDS by request

Delanzomib

CAS Number: 847499-27-8

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Loading RDKit molecule structure...
InChIKey: SJFBTAPEPRWNKH-CCKFTAQKSA-NC21H28BN3O5 | MW 413.3

Chemical Absolute Identifiers

CAS Number

847499-27-8

PubChem CID

24800541

Molecular Formula

C21H28BN3O5

Molecular Weight

413.3 g/mol

Exact Mass

413.212201

InChIKey

SJFBTAPEPRWNKH-CCKFTAQKSA-N

IUPAC Name

[(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridine-2-carbonyl)amino]butanoyl]amino]-3-methylbutyl]boronic acid

SMILES String

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccc(-c2ccccc2)n1)[C@@H](C)O)B(O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Delanzomib (CAS 847499-27-8) is listed in the Advanced Chemicals portfolio, with molecular formula C21H28BN3O5 and molecular weight 413. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle, boronic-acid-related structure.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Boronic Acids and EstersSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Proteasome Macropain subunit MB1 (Homo sapiens) — 3 assays; Cathepsin G (Homo sapiens) — 4 assays; Proteasome Macropain subunit (Homo sapiens) — 2 assays; Chymase (Homo sapiens) — 2 assays; Neutrophil elastase (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Proteasome Macropain subunit MB1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.82

Experimental evidence source: ChEMBL

Cathepsin G

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 2 documents · best pChEMBL 7.87

Experimental evidence source: ChEMBL

Proteasome Macropain subunit

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.46

Experimental evidence source: ChEMBL

Chymase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.45

Experimental evidence source: ChEMBL

Neutrophil elastase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.45

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Delanzomib

Names & Synonyms

CEP 18770NPH 007098delanzomibumCIP 18770CT 47098
Show all synonyms
Boronic acid, ((1R)-1-(((2S,3R)-3-hydroxy-1-oxo-2-(((6-phenyl-2-pyridinyl)carbonyl)amino)butyl)amino)-3-methylbutyl)-[(1R)-1-[(2S,3R)-3-hydroxy-2-[(6-phenylpyridin-2-yl)formamido]butanamido]-3-methylbutyl]boronic acid((1R)-1-((2S,3R)-3-HYDROXY-2-(6-PHENYLPYRIDINE-2-CARBOXAMIDO)BUTANAMIDO)-3-METHYLBUTYL)BORONIC ACID((1R)-1-((2S,3R)-3-hydroxy-2-((6-phenylpyridin-2-yl)formamido)butanamido)-3-methylbutyl)boronic acidProteasome Inhibitor CEP 18770Delanzomib (CEP-18770)((R)-1-((2S,3R)-3-Hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutyl)boronic acidDelanzomib [USAN:INN][(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acidDelanzomib [USAN]Delanzomib (USAN)CEP-18770 (Delanzomib)((1R)-1-(((2s,3r)-3-hydroxy-2-(((6-phenylpyridin-2-yl)carbonyl)amino)-1-oxobutyl)amino)-3-methylbutyl)boronic acidBORONIC ACID, B-((1R)-1-(((2S,3R)-3-HYDROXY-1-OXO-2-(((6-PHENYL-2-PYRIDINYL)CARBONYL)AMINO)BUTYL)AMINO)-3-METHYLBUTYL)-
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID901025656CHEMBL ID: CHEMBL270515CHEBI ID: CHEBI:141530UNII: 6IF28942WODRUGBANK ID: DB11956KEGG ID: D10110METABOLOMICS WORKBENCH ID: 153029NCI THESAURUS CODE: C74075WIKIDATA ID: Q27264956
Literature & Patent References
DOI 10.6019/EOS300108ECBD screening data for assay EOS300108DOI 10.1021/acs.jmedchem.0c01640Proteases and Their Modulators in Cancer Therapy: Challenges and Opportunities.DOI 10.6019/EOS300033ECBD screening data for assay EOS300033PMID 33656892Proteases and Their Modulators in Cancer Therapy: Challenges and Opportunities.DOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.ejmech.2019.111646Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.PMID 31521028Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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  1. 1We review the CAS identity, quantity, and documentation request.
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  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

B-((1R)-3-Methyl-1-(((2R)-1-oxo-3-phenyl-2-((2-pyrazinylcarbonyl)amino)propyl)amino)butyl)boronic acidCAS 1132709-15-9
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acidCAS 1132709-14-8
IxazomibCAS 1072833-77-2
Bortezomib boronic anhydrideCAS 390800-88-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1132709-15-9B-((1R)-3-Methyl-1-(((2R)-1-oxo-3-phenyl-2-((2-pyrazinylcarbonyl)amino)propyl)amino)butyl)boronic acidCAS 1132709-14-8((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acidCAS 179324-69-7BortezomibCAS 1072833-77-2IxazomibCAS 520-36-5ApigeninCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 847499-27-8

What are the key identifiers for Delanzomib (CAS 847499-27-8)?

Delanzomib is identified by CAS 847499-27-8, with molecular formula C21H28BN3O5, molecular weight 413.3, InChIKey SJFBTAPEPRWNKH-CCKFTAQKSA-N.

Does CAS 847499-27-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Proteasome Macropain subunit MB1, Cathepsin G, Proteasome Macropain subunit, Chymase, Neutrophil elastase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 847499-27-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Delanzomib?

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Is CAS 847499-27-8 available for quotation?

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