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Home/Compounds/CAS 122-11-2
Formula C12H14N4O4SMW 310.33Research-use catalog entryCOA/SDS by request

Sulfadimethoxine

CAS Number: 122-11-2

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1 g
Purity
98+%
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1 mg
Purity
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2000 l
Purity
96% at 85℃; for 6 h; Large scale (2),在2000L反应器中加入600kg甲醇,缩合产物348.5kg,20%苛性钠440kg,搅拌温度至85℃回流6h。 跟踪反应完成后,冷却至10℃以下,滴加20%盐酸溶
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25 mg
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Loading RDKit molecule structure...
InChIKey: ZZORFUFYDOWNEF-UHFFFAOYSA-NC12H14N4O4S | MW 310.33

Chemical Absolute Identifiers

CAS Number

122-11-2

PubChem CID

5323

Molecular Formula

C12H14N4O4S

Molecular Weight

310.33 g/mol

Exact Mass

310.073576

InChIKey

ZZORFUFYDOWNEF-UHFFFAOYSA-N

IUPAC Name

4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide

SMILES String

COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC

Physical Properties

Melting Point

203.5 °C

Water Solubility

343 mg/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Sulfadimethoxine (CAS 122-11-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C12H14N4O4S and molecular weight 310. 33 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cytochrome P450 3A4 (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 2 assays; Prostaglandin G/H synthase 1 (Homo sapiens) — 2 assays; Thromboxane A2 receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.4

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Prostaglandin G/H synthase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Thromboxane A2 receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Including any incompatibility.
  • Close tightly.
  • Store in a well-ventilated area.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Sulfadimethoxine

Names & Synonyms

SulphadimethoxineAlbonSulfadimethoxydiazineMadribonSulfadimetoxina
Show all synonyms
Benzenesulfonamide, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamideSulfadimethoxinum2,6-Dimethoxy-4-sulfanilamidopyrimidine2,4-Dimethoxy-6-sulfanilamido-1,3-diazine6-Sulfanilamido-2,4-dimethoxypyrimidineDi-MethoxSULFAMED-G4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide2,6-Dimethoxy-4-(p-aminobenzenesulfonamido)pyrimidineN(sup 1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamideN(1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamideSulforalSulfaMed
External Identifiers
EC NUMBER: 204-523-7DSSTOX SUBSTANCE ID: DTXSID1023607CHEMBL ID: CHEMBL62193CHEBI ID: CHEBI:32161UNII: 30CPC5LDEXDRUGBANK ID: DB06150HMDB ID: HMDB0015621KEGG ID: D01142METABOLOMICS WORKBENCH ID: 43660NCI THESAURUS CODE: C76975PHARMGKB ID: PA165958357RXCUI: 10172WIKIDATA ID: Q4921678
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

SulfamethoxypyridazineCAS 80-35-3
SulfamethoxazoleCAS 723-46-6
SulfaclozineCAS 102-65-8
SulfamethazineCAS 57-68-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 80-35-3SulfamethoxypyridazineCAS 723-46-6SulfamethoxazoleCAS 102-65-8SulfaclozineCAS 57-68-1SulfamethazineCAS 100-33-4PentamidineCAS 111974-69-7QuetiapineCAS 112574-44-4NitrofurazoneCAS 22204-53-1NaproxenCAS 1156-19-0TolazamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

RFQ questions for CAS 122-11-2

What are the key identifiers for Sulfadimethoxine (CAS 122-11-2)?

Sulfadimethoxine is identified by CAS 122-11-2, with molecular formula C12H14N4O4S, molecular weight 310.33, InChIKey ZZORFUFYDOWNEF-UHFFFAOYSA-N.

Does CAS 122-11-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cytochrome P450 3A4, Alpha-1A adrenergic receptor, Muscarinic acetylcholine receptor M1, Prostaglandin G/H synthase 1, Thromboxane A2 receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 122-11-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Sulfadimethoxine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 122-11-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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