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Home/Compounds/CAS 723-46-6
Formula C10H11N3O3SMW 253.28Research-use catalog entryCOA/SDS by request

Sulfamethoxazole

CAS Number: 723-46-6

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Loading RDKit molecule structure...
InChIKey: JLKIGFTWXXRPMT-UHFFFAOYSA-NC10H11N3O3S | MW 253.28

Chemical Absolute Identifiers

CAS Number

723-46-6

PubChem CID

5329

Molecular Formula

C10H11N3O3S

Molecular Weight

253.28 g/mol

Exact Mass

253.052112

InChIKey

JLKIGFTWXXRPMT-UHFFFAOYSA-N

IUPAC Name

4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide

SMILES String

CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N

Physical Properties

Appearance

Crystals or white powder. (NTP, 1992)

pKa

1

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Sulfamethoxazole (CAS 723-46-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C10H11N3O3S and molecular weight 253. 28 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Human immunodeficiency virus type 1 protease (Human immunodeficiency virus 1) — 4 assays; Endothelin-1 receptor (Rattus norvegicus) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 4 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 3 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Human immunodeficiency virus type 1 protease

Human immunodeficiency virus 1 · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

Endothelin-1 receptor

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.4

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 4.87

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 1A

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Including any incompatibility.
  • Close tightly.
  • Store in a well-ventilated area.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction stability.
  • Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Sulfamethoxazole

Names & Synonyms

GantanolSulphamethoxazoleSulfisomezoleSulfamethoxazol4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
Show all synonyms
RadonilSinominSulfamethylisoxazole4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamideSulfamethalazoleAzo-gantanolUrobakSulfamethoxizoleGantanol-DSRo 4-2130SulfametoxazolGamazole3-Sulfanilamido-5-methylisoxazoleSulfamethoxazolum
External Identifiers
EC NUMBER: 211-963-3EC NUMBER: 656-929-2DSSTOX SUBSTANCE ID: DTXSID8026064CHEMBL ID: CHEMBL443CHEBI ID: CHEBI:9332UNII: JE42381TNVDRUGBANK ID: DB01015HMDB ID: HMDB0015150KEGG ID: C07315KEGG ID: D00447METABOLOMICS WORKBENCH ID: 43260NCI THESAURUS CODE: C47737PHARMGKB ID: PA451544RXCUI: 10180WIKIDATA ID: Q415843
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1039/D4MD00508BAdvances in antibacterial agents for <i>Mycobacterium fortuitum</i>.PMID 39493226Advances in antibacterial agents for <i>Mycobacterium fortuitum</i>.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.3c02355Design, Synthesis, and Biological Evaluation of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against <i>Staphylococcus aureus</i>.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38466654Design, Synthesis, and Biological Evaluation of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against <i>Staphylococcus aureus</i>.DOI 10.1016/j.ejmech.2023.115701Heterocyclic pyrimidine derivatives as promising antibacterial agents.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

SulfamethazineCAS 57-68-1
SulfamethoxypyridazineCAS 80-35-3
SulfadimethoxineCAS 122-11-2
SulfaclozineCAS 102-65-8
PhthalylsulfacetamideCAS 131-69-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 57-68-1SulfamethazineCAS 80-35-3SulfamethoxypyridazineCAS 122-11-2SulfadimethoxineCAS 102-65-8SulfaclozineCAS 1072-67-93-Amino-5-methylisoxazoleCAS 100643-71-8DesloratadineCAS 107724-20-9EplerenoneCAS 111974-69-7QuetiapineCAS 169590-42-5CelecoxibCAS 58-14-0Pyrimethamine

RFQ questions for CAS 723-46-6

What are the key identifiers for Sulfamethoxazole (CAS 723-46-6)?

Sulfamethoxazole is identified by CAS 723-46-6, with molecular formula C10H11N3O3S, molecular weight 253.28, InChIKey JLKIGFTWXXRPMT-UHFFFAOYSA-N.

Does CAS 723-46-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Human immunodeficiency virus type 1 protease, Endothelin-1 receptor, Alpha-1A adrenergic receptor, 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 723-46-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Sulfamethoxazole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 723-46-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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