- Package
- 10 mg
- Purity
- 98%
- Price
- Request review
- Availability
- Shipping review required
- Delivery
- Shipping review required
CAS Number: 1269440-17-6
Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.
Available options
Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.
CAS Number
1269440-17-6
PubChem CID
50922675
Molecular Formula
C22H27ClFN7O4S
Molecular Weight
540 g/mol
Exact Mass
539.151779
InChIKey
CMJCXYNUCSMDBY-ZDUSSCGKSA-N
IUPAC Name
methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate
SMILES String
COC(=O)N[C@@H](C)CNc1nccc(-c2cn(C(C)C)nc2-c2cc(Cl)cc(NS(C)(=O)=O)c2F)n1
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Encorafenib (CAS 1269440-17-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C22H27ClFN7O4S and molecular weight 540. 00 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Serine/threonine-protein kinase B-raf (Homo sapiens) — 11 assays; Mitogen-activated protein kinase 14 (Homo sapiens) — 2 assays; Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Serine/threonine-protein kinase B-raf
Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 10 documents · best pChEMBL 9.52
Experimental evidence source: ChEMBL
Mitogen-activated protein kinase 14
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.66
Experimental evidence source: ChEMBL
Gamma-aminobutyric acid receptor subunit alpha-1
Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.64
Experimental evidence source: ChEMBL
5-hydroxytryptamine receptor 2B
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.55
Experimental evidence source: ChEMBL
5-hydroxytryptamine receptor 1A
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Encorafenib is identified by CAS 1269440-17-6, with molecular formula C22H27ClFN7O4S, molecular weight 540, InChIKey CMJCXYNUCSMDBY-ZDUSSCGKSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Serine/threonine-protein kinase B-raf, Mitogen-activated protein kinase 14, Gamma-aminobutyric acid receptor subunit alpha-1, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 1A. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.