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Home/Compounds/CAS 140-64-7
Formula C23H36N4O10S2MW 592.7Research-use catalog entryCOA/SDS by request

Pentamidine Isethionate

CAS Number: 140-64-7

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Available Options

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1 g
Purity
97%
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10 g
Purity
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250 mg
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5 g
Purity
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Loading RDKit molecule structure...
InChIKey: YBVNFKZSMZGRAD-UHFFFAOYSA-NC23H36N4O10S2 | MW 592.7

Chemical Absolute Identifiers

CAS Number

140-64-7

PubChem CID

8813

Molecular Formula

C23H36N4O10S2

Molecular Weight

592.7 g/mol

Exact Mass

592.187286

InChIKey

YBVNFKZSMZGRAD-UHFFFAOYSA-N

IUPAC Name

4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;bis(2-hydroxyethanesulfonic acid)

SMILES String

C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N.C(CS(=O)(=O)O)O.C(CS(=O)(=O)O)O

Physical Properties

Melting Point

187.78–192.22 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Pentamidine Isethionate (CAS 140-64-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C23H36N4O10S2 and molecular weight 592. 70 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Pyruvate kinase PKM (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Rattus norvegicus) — 2 assays; Thrombopoietin (Homo sapiens) — 2 assays; Serine/threonine-protein kinase mTOR (Homo sapiens) — 2 assays; Geminin (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Pyruvate kinase PKM

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.3

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.4

Experimental evidence source: ChEMBL

Thrombopoietin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.1

Experimental evidence source: ChEMBL

Serine/threonine-protein kinase mTOR

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.98

Experimental evidence source: ChEMBL

Geminin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.75

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Pentamidine Isethionate

Names & Synonyms

Pentamidine diisethionate4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)Pentamidine isetionatePentacarinatNebupent
Show all synonyms
Pentamidine diisetionateDiamidineLomidinPneumopentLomidine isoethionatePENTAMRP 2512Pentamidini isetionasMB 800WR 49314,4'-Diamidino-alpha,omega-diphenoxypentane isethionate2512 R.P.M & B 800R.P. 25124,4'-Diamidinodiphenoxypentane di(beta-hydroxyethanesulfonate)
External Identifiers
EC NUMBER: 205-424-1DSSTOX SUBSTANCE ID: DTXSID5023796CHEMBL ID: CHEMBL361506CHEBI ID: CHEBI:7977UNII: V2P3K60DA2KEGG ID: D00834NCI THESAURUS CODE: C29349RXCUI: 7995WIKIDATA ID: Q26841221
Experimental Spectrum References
ATR-IR SpectraUV Spectra
Literature & Patent References
DOI 10.6019/EOS300108ECBD screening data for assay EOS300108DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replicationDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.ejmech.2018.02.087Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives.PMID 29567458Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 140-64-7

What are the key identifiers for Pentamidine Isethionate (CAS 140-64-7)?

Pentamidine Isethionate is identified by CAS 140-64-7, with molecular formula C23H36N4O10S2, molecular weight 592.7, InChIKey YBVNFKZSMZGRAD-UHFFFAOYSA-N.

Does CAS 140-64-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Pyruvate kinase PKM, Muscarinic acetylcholine receptor M1, Thrombopoietin, Serine/threonine-protein kinase mTOR, Geminin. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 140-64-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Pentamidine Isethionate?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 140-64-7 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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