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Home/Compounds/CAS 14270-73-6
Formula C28H26N2O5MW 470.5Research-use catalog entryCOA/SDS by request

2'-Deoxy-5'-O-(triphenylmethyl)uridine

CAS Number: 14270-73-6

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Loading RDKit molecule structure...
InChIKey: JJJNFNLUKYZAKI-BFLUCZKCSA-NC28H26N2O5 | MW 470.5

Chemical Absolute Identifiers

CAS Number

14270-73-6

PubChem CID

13711960

Molecular Formula

C28H26N2O5

Molecular Weight

470.5 g/mol

Exact Mass

470.184172

InChIKey

JJJNFNLUKYZAKI-BFLUCZKCSA-N

IUPAC Name

1-[(2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

SMILES String

O=c1ccn([C@H]2C[C@H](O)[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

2'-Deoxy-5'-O-(triphenylmethyl)uridine (CAS 14270-73-6) is listed in the Life Science portfolio, with molecular formula C28H26N2O5 and molecular weight 470. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchNucleic Acid ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: dUTP pyrophosphatase (Plasmodium falciparum 3D7) — 3 assays; Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

dUTP pyrophosphatase

Plasmodium falciparum 3D7 · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.75

Experimental evidence source: ChEMBL

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 4.75

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

2'-Deoxy-5'-O-(triphenylmethyl)uridine

Names & Synonyms

5'-O-Trityl-2'-deoxyuridine5/'-O-Trityl-2/'-deoxyuridine1-((2R,4S,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione1-[(2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione2'-Deoxy-5'-O-trityluridine
Show all synonyms
1-[(2R,4S,5R)-4-hydroxy-5-[(triphenylmethoxy)methyl]oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione5'-O-Triphenylmethyl-2'-deoxyuridine5'-O-Trt-2'-deoxyuridine5'-Trt-2'-dU2'-deoxy 5'-O-trityluridine5'-O-Trityl-2'-deoxyur-idine1-(4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione1-((2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione1-((2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID40547404CHEMBL ID: CHEMBL438428WIKIDATA ID: Q82425603
Literature & Patent References
DOI 10.1016/j.ejmech.2013.04.034In search of flavivirus inhibitors: evaluation of different tritylated nucleoside analogues.PMID 23721953In search of flavivirus inhibitors: evaluation of different tritylated nucleoside analogues.DOI 10.1021/jm201628yDiscovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.PMID 22339362Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.DOI 10.1016/j.bmc.2011.02.012β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.PMID 21411327β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.DOI 10.1016/j.ejmech.2008.05.018Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of Plasmodium falciparum dUTP nucleotidohydrolase.PMID 18619713Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of Plasmodium falciparum dUTP nucleotidohydrolase.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

1-(2-Deoxy-5-O-(triphenylmethyl)pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dioneCAS 7791-71-1
5'-O-(Bis(4-methoxyphenyl)phenylmethyl)uridineCAS 81246-79-9
5'-O-tert-ButyldimethylsilylthymidineCAS 40733-28-6
5'-Thymidylic acidCAS 365-07-1
FloxuridineCAS 50-91-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 7791-71-11-(2-Deoxy-5-O-(triphenylmethyl)pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dioneCAS 81246-79-95'-O-(Bis(4-methoxyphenyl)phenylmethyl)uridineCAS 40733-28-65'-O-tert-ButyldimethylsilylthymidineCAS 365-07-15'-Thymidylic acidCAS 50-91-9FloxuridineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 14270-73-6

What are the key identifiers for 2'-Deoxy-5'-O-(triphenylmethyl)uridine (CAS 14270-73-6)?

2'-Deoxy-5'-O-(triphenylmethyl)uridine is identified by CAS 14270-73-6, with molecular formula C28H26N2O5, molecular weight 470.5, InChIKey JJJNFNLUKYZAKI-BFLUCZKCSA-N.

Does CAS 14270-73-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with dUTP pyrophosphatase, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 14270-73-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 2'-Deoxy-5'-O-(triphenylmethyl)uridine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 14270-73-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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