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Home/Compounds/CAS 21763-80-4
Formula C19H18O7MW 358.3Research-use catalog entryCOA/SDS by request

5-Hydroxy-6,7,3',4'-Tetramethoxyflavone

CAS Number: 21763-80-4

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Available Options

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1 mg
Purity
98%
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Loading RDKit molecule structure...
InChIKey: QEWSAPKRFOFQIU-UHFFFAOYSA-NC19H18O7 | MW 358.3

Chemical Absolute Identifiers

CAS Number

21763-80-4

PubChem CID

152430

Molecular Formula

C19H18O7

Molecular Weight

358.3 g/mol

Exact Mass

358.105253

InChIKey

QEWSAPKRFOFQIU-UHFFFAOYSA-N

IUPAC Name

2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one

SMILES String

COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

5-Hydroxy-6,7,3',4'-Tetramethoxyflavone (CAS 21763-80-4) is listed in the Advanced Chemicals portfolio, with molecular formula C19H18O7 and molecular weight 358. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cytochrome P450 1A2 (Homo sapiens) — 2 assays; Cytochrome P450 1A1 (Homo sapiens) — 3 assays; Cytochrome P450 1B1 (Homo sapiens) — 2 assays; Delta-type opioid receptor (Homo sapiens) — 3 assays; Cytochrome P450 2C19 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cytochrome P450 1A2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.11

Experimental evidence source: ChEMBL

Cytochrome P450 1A1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.86

Experimental evidence source: ChEMBL

Cytochrome P450 1B1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.6

Experimental evidence source: ChEMBL

Delta-type opioid receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.51

Experimental evidence source: ChEMBL

Cytochrome P450 2C19

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

5-Hydroxy-6,7,3',4'-Tetramethoxyflavone

Names & Synonyms

5-Hydroxy-3',4',6,7-tetramethoxyflavoneHTMF4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-5-Desmethylsinensetin2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one
Show all synonyms
5-demethylsinensetin6-Hydroxyluteolin 6,7,3',4'-tetramethyl ether2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-oneSANTAFLAVONE3'-O-methyl-eupatorin3'-O-METHYLEUPATORIN2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one5-hydroxy-3',4',6,7-tetramethoxy flavonoid2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one #
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID50176163CHEMBL ID: CHEMBL226508UNII: MRF3C7FE9GMETABOLOMICS WORKBENCH ID: 24326WIKIDATA ID: Q83046487
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115791Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery.PMID 37683361Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery.DOI 10.1016/j.bmc.2019.115180Artemisia: a promising plant for the treatment of cancer.PMID 31784199Artemisia: a promising plant for the treatment of cancer.DOI 10.1039/C7MD00388AIdentification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy <i>via</i> screening of a natural product repository.PMID 30108931Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy <i>via</i> screening of a natural product repository.DOI 10.1021/acs.jnatprod.5b00218Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors.PMID 26035635Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

EupatilinCAS 22368-21-4
JaceosidinCAS 18085-97-7
5-DemethylnobiletinCAS 2174-59-6
NepetinCAS 520-11-6
IsosinensetinCAS 17290-70-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 22368-21-4EupatilinCAS 18085-97-7JaceosidinCAS 2174-59-65-DemethylnobiletinCAS 520-11-6NepetinCAS 17290-70-9IsosinensetinCAS 2543-94-4PhellopterinCAS 82-02-0KhellinCAS 22916-47-8MiconazoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 21763-80-4

What are the key identifiers for 5-Hydroxy-6,7,3',4'-Tetramethoxyflavone (CAS 21763-80-4)?

5-Hydroxy-6,7,3',4'-Tetramethoxyflavone is identified by CAS 21763-80-4, with molecular formula C19H18O7, molecular weight 358.3, InChIKey QEWSAPKRFOFQIU-UHFFFAOYSA-N.

Does CAS 21763-80-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cytochrome P450 1A2, Cytochrome P450 1A1, Cytochrome P450 1B1, Delta-type opioid receptor, Cytochrome P450 2C19. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 21763-80-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 5-Hydroxy-6,7,3',4'-Tetramethoxyflavone?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 21763-80-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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