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Home/Compounds/CAS 22916-47-8
Formula C18H14Cl4N2OMW 416.1Research-use catalog entryCOA/SDS by request

Miconazole

CAS Number: 22916-47-8

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Loading RDKit molecule structure...
InChIKey: BYBLEWFAAKGYCD-UHFFFAOYSA-NC18H14Cl4N2O | MW 416.1

Chemical Absolute Identifiers

CAS Number

22916-47-8

PubChem CID

4189

Molecular Formula

C18H14Cl4N2O

Molecular Weight

416.1 g/mol

Exact Mass

415.983074

InChIKey

BYBLEWFAAKGYCD-UHFFFAOYSA-N

IUPAC Name

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

SMILES String

C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl

Physical Properties

Melting Point

159–163 °C

Water Solubility

7.63 × 10⁻⁴ g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Miconazole (CAS 22916-47-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C18H14Cl4N2O and molecular weight 416. 10 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cytochrome P450 2C19 (Homo sapiens) — 8 assays; Cytochrome P450 3A4 (Homo sapiens) — 12 assays; Cytochrome P450 2C9 (Homo sapiens) — 5 assays; Sodium-dependent serotonin transporter (Homo sapiens) — 2 assays; Cytochrome P450 2J2 (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cytochrome P450 2C19

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 6 documents · best pChEMBL 10.7

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 10 documents · best pChEMBL 9

Experimental evidence source: ChEMBL

Cytochrome P450 2C9

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 4 documents · best pChEMBL 6.94

Experimental evidence source: ChEMBL

Sodium-dependent serotonin transporter

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.38

Experimental evidence source: ChEMBL

Cytochrome P450 2J2

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 6.24

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Miconazole

Names & Synonyms

Daktarin IVMiconazolMiconazoloMiconazolum1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
Show all synonyms
DaktarinOravig1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-DermazoleDumicoatLoramyc1-(2,4-Dichloro-beta-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)imidazole1-(2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl)-1H-imidazole1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-1h-imidazole
External Identifiers
EC NUMBER: 245-324-5DSSTOX SUBSTANCE ID: DTXSID6023319CHEMBL ID: CHEMBL91CHEBI ID: CHEBI:82892UNII: 7NNO0D7S5MDRUGBANK ID: DB01110HMDB ID: HMDB0015242KEGG ID: D00416METABOLOMICS WORKBENCH ID: 43338NCI THESAURUS CODE: C62048PHARMGKB ID: PA450494RXCUI: 6932WIKIDATA ID: Q410534Monistat-3
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.bmc.2025.118069Current strategies in design and synthesis of antifungals hybrid and chimeric diazine derivatives.DOI 10.1021/acs.jmedchem.5c00056Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.PMID 39818112Current strategies in design and synthesis of antifungals hybrid and chimeric diazine derivatives.PMID 40512599Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.4c00303Identification of Potent and Selective Inhibitors of <i>Acanthamoeba</i>: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target.DOI 10.1021/acs.jmedchem.4c00593Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

EconazoleCAS 27220-47-9
Econazole NitrateCAS 24169-02-6
Fenticonazole NitrateCAS 73151-29-8
Butoconazole NitrateCAS 64872-77-1
CroconazoleCAS 77175-51-0

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 23593-75-1ClotrimazoleCAS 27220-47-9EconazoleCAS 24169-02-6Econazole NitrateCAS 73151-29-8Fenticonazole NitrateCAS 21829-25-4NifedipineCAS 94-99-52,4-Dichlorobenzyl chlorideCAS 24155-42-8(+-)-alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 22916-47-8

What are the key identifiers for Miconazole (CAS 22916-47-8)?

Miconazole is identified by CAS 22916-47-8, with molecular formula C18H14Cl4N2O, molecular weight 416.1, InChIKey BYBLEWFAAKGYCD-UHFFFAOYSA-N.

Does CAS 22916-47-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cytochrome P450 2C19, Cytochrome P450 3A4, Cytochrome P450 2C9, Sodium-dependent serotonin transporter, Cytochrome P450 2J2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 22916-47-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Miconazole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 22916-47-8 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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