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Home/Compounds/CAS 27220-47-9
Formula C18H15Cl3N2OMW 381.7Research-use catalog entryCOA/SDS by request

Econazole

CAS Number: 27220-47-9

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Loading RDKit molecule structure...
InChIKey: LEZWWPYKPKIXLL-UHFFFAOYSA-NC18H15Cl3N2O | MW 381.7

Chemical Absolute Identifiers

CAS Number

27220-47-9

PubChem CID

3198

Molecular Formula

C18H15Cl3N2O

Molecular Weight

381.7 g/mol

Exact Mass

380.024996

InChIKey

LEZWWPYKPKIXLL-UHFFFAOYSA-N

IUPAC Name

1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole

SMILES String

C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl

Physical Properties

Water Solubility

1.48 × 10⁻³ g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Econazole (CAS 27220-47-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C18H15Cl3N2O and molecular weight 381. 70 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cytochrome P450 3A4 (Homo sapiens) — 3 assays; Sodium-dependent serotonin transporter (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M3 (Homo sapiens) — 2 assays; Delta-type opioid receptor (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.3

Experimental evidence source: ChEMBL

Sodium-dependent serotonin transporter

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.65

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M3

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.42

Experimental evidence source: ChEMBL

Delta-type opioid receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.29

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.2

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides.

Disposal

  • Waste product: Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional institution with a waste disposal license to handle this substance.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Econazole

Names & Synonyms

EconazolumEconazol(+-)-Econazole1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole1-{2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
Show all synonyms
1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-econazoloEkonazoleGynoPevarilGyno PevarilGyno Pevaryl1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazole1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)imidazoleGyno Pervaryl 150Gyno-Pevaril1-(2-((4-Chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
External Identifiers
EC NUMBER: 248-341-6DSSTOX SUBSTANCE ID: DTXSID2029872CHEMBL ID: CHEMBL808CHEBI ID: CHEBI:82873UNII: 6Z1Y2V4A7MDRUGBANK ID: DB01127HMDB ID: HMDB0015259KEGG ID: C08068KEGG ID: D03936METABOLOMICS WORKBENCH ID: 43352NCI THESAURUS CODE: C61740PHARMGKB ID: PA164746010RXCUI: 3743WIKIDATA ID: Q417141
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116379Advances in TRPV6 inhibitors for tumors by targeted therapies: Macromolecular proteins, synthetic small molecule compounds, and natural compounds.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38588625Advances in TRPV6 inhibitors for tumors by targeted therapies: Macromolecular proteins, synthetic small molecule compounds, and natural compounds.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.1021/acsmedchemlett.1c00538Water-Soluble Nystatin and Derivative.PMID 35178173Water-Soluble Nystatin and Derivative.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Econazole NitrateCAS 24169-02-6
MiconazoleCAS 22916-47-8
Fenticonazole NitrateCAS 73151-29-8
Butoconazole NitrateCAS 64872-77-1
CroconazoleCAS 77175-51-0

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 24169-02-6Econazole NitrateCAS 22916-47-8MiconazoleCAS 73151-29-8Fenticonazole NitrateCAS 23593-75-1ClotrimazoleCAS 21829-25-4NifedipineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 27220-47-9

What are the key identifiers for Econazole (CAS 27220-47-9)?

Econazole is identified by CAS 27220-47-9, with molecular formula C18H15Cl3N2O, molecular weight 381.7, InChIKey LEZWWPYKPKIXLL-UHFFFAOYSA-N.

Does CAS 27220-47-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cytochrome P450 3A4, Sodium-dependent serotonin transporter, Muscarinic acetylcholine receptor M3, Delta-type opioid receptor, Muscarinic acetylcholine receptor M1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 27220-47-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Econazole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 27220-47-9 available for quotation?

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