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Home/Compounds/CAS 3056-17-5
Formula C10H12N2O4MW 224.21Research-use catalog entryCOA/SDS by request

Stavudine

CAS Number: 3056-17-5

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Loading RDKit molecule structure...
InChIKey: XNKLLVCARDGLGL-JGVFFNPUSA-NC10H12N2O4 | MW 224.21

Chemical Absolute Identifiers

CAS Number

3056-17-5

PubChem CID

18283

Molecular Formula

C10H12N2O4

Molecular Weight

224.21 g/mol

Exact Mass

224.079707

InChIKey

XNKLLVCARDGLGL-JGVFFNPUSA-N

IUPAC Name

1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione

SMILES String

CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO

Physical Properties

Appearance

2',3'-didehydro-3'-deoxythymidine appears as white crystalline solid or powder. Odorless. (NTP, 1992)

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Stavudine (CAS 3056-17-5) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C10H12N2O4 and molecular weight 224. 21 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) — 6 assays; RecQ-like DNA helicase BLM (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 6 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 5 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 5 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Human immunodeficiency virus type 1 reverse transcriptase

Human immunodeficiency virus 1 · SINGLE PROTEIN · 6 qualifying assays · 5 documents · best pChEMBL 7.3

Experimental evidence source: ChEMBL

RecQ-like DNA helicase BLM

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.1

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 1 documents · best pChEMBL 4.52

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 1A

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-2A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction stability.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Stavudine

Names & Synonyms

sanilvudineZerit2',3'-Didehydro-3'-deoxythymidineEstavudinaStavudinum
Show all synonyms
Thymidine, 2',3'-didehydro-3'-deoxy-Zerit Xr1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dioneD 4T (nucleoside)3'-Deoxy-2'-thymidinene2',3'-Didehydro-3'-deoxythimidine3'-Deoxy-2',3'-didehydrothymidineBMY 27857Stavudine (d4T)Dideoxydidehydrothymidine1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymineStavudine (dt4)2'-Thymidinene, 3'-deoxy-1-[(2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL]-5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE
External Identifiers
EC NUMBER: 641-374-0DSSTOX SUBSTANCE ID: DTXSID1023819CHEMBL ID: CHEMBL991CHEBI ID: CHEBI:63581UNII: BO9LE4QFZFDRUGBANK ID: DB00649HMDB ID: HMDB0014787KEGG ID: C07312KEGG ID: D00445METABOLOMICS WORKBENCH ID: 42969NCI THESAURUS CODE: C1428PHARMGKB ID: PA451494WIKIDATA ID: Q423984
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.3c02022Antiviral Activity of Lipophilic Nucleoside Tetraphosphate Compounds.PMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38345794Antiviral Activity of Lipophilic Nucleoside Tetraphosphate Compounds.DOI 10.1021/acs.jmedchem.3c00755Pronucleotides of 2',3'-Dideoxy-2',3'-Didehydrothymidine as Potent Anti-HIV Compounds.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37647547Pronucleotides of 2',3'-Dideoxy-2',3'-Didehydrothymidine as Potent Anti-HIV Compounds.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

DideoxycytidineCAS 7481-89-2
EmtricitabineCAS 143491-57-0
LamivudineCAS 134678-17-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 59277-89-32-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-oneCAS 60142-96-3GabapentinCAS 30516-87-1ZidovudineCAS 134678-17-4LamivudineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 3056-17-5

What are the key identifiers for Stavudine (CAS 3056-17-5)?

Stavudine is identified by CAS 3056-17-5, with molecular formula C10H12N2O4, molecular weight 224.21, InChIKey XNKLLVCARDGLGL-JGVFFNPUSA-N.

Does CAS 3056-17-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Human immunodeficiency virus type 1 reverse transcriptase, RecQ-like DNA helicase BLM, Alpha-1A adrenergic receptor, 5-hydroxytryptamine receptor 1A, Alpha-2A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 3056-17-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Stavudine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 3056-17-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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