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Home/Compounds/CAS 328-38-1
Formula C6H13NO2MW 131.17Research-use catalog entryCOA/SDS by request

D-Leucine

CAS Number: 328-38-1

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Loading RDKit molecule structure...
InChIKey: ROHFNLRQFUQHCH-RXMQYKEDSA-NC6H13NO2 | MW 131.17

Chemical Absolute Identifiers

CAS Number

328-38-1

PubChem CID

439524

Molecular Formula

C6H13NO2

Molecular Weight

131.17 g/mol

Exact Mass

131.094629

InChIKey

ROHFNLRQFUQHCH-RXMQYKEDSA-N

IUPAC Name

(2R)-2-amino-4-methylpentanoic acid

SMILES String

CC(C)C[C@H](C(=O)O)N

Physical Properties

Melting Point

293.0 °C

Water Solubility

21.5 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

D-Leucine (CAS 328-38-1) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C6H13NO2 and molecular weight 131. 17 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Large neutral amino acids transporter small subunit 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Large neutral amino acids transporter small subunit 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

D-Leucine

Names & Synonyms

Leucine, D-(R)-(-)-LeucineD-LeuD-2-Amino-4-methylvaleric acidLeucine,d
Show all synonyms
D-LeucinD-LeuzinD-LEUCINELEUCINE, D-(R)-4-METHYL-2-AMINOPENTANOIC ACIDD-leucine zwitterion(2R)-2-amino-4-methylpentanoateD-2-Amino-4-methylvalerateH-D-Leu-OH(R)-Leucine(R)-2-Amino-4-methylpentanoic acidD-Homo-valineD-Leu-OH(2R)-2-azaniumyl-4-methylpentanoateD-2-Amino-4-methylpentanoic acid
External Identifiers
EC NUMBER: 206-327-7DSSTOX SUBSTANCE ID: DTXSID6046347CHEMBL ID: CHEMBL1232258CHEBI ID: CHEBI:28225UNII: 965COD96YADRUGBANK ID: DB01746HMDB ID: HMDB0013773KEGG ID: C01570METABOLOMICS WORKBENCH ID: 51630
Experimental Spectrum References
13C NMR Spectra1D NMR SpectraFTIR SpectraRaman Spectra — Bio-Rad Laboratories, Inc.
Literature & Patent References
DOI 10.1021/acs.jmedchem.8b01007Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).PMID 30048132Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).DOI 10.1074/jbc.m009462200Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.PMID 11278508Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Leucine methyl ester hydrochlorideCAS 7517-19-3
L-(+)-CysteineCAS 52-90-4
L-Glutamic AcidCAS 56-86-0
DL-Glutamic acidCAS 617-65-2
DL-GlutamineCAS 56-85-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 7517-19-3Leucine methyl ester hydrochlorideCAS 52-90-4L-(+)-CysteineCAS 56-86-0L-Glutamic AcidCAS 617-65-2DL-Glutamic acidCAS 56-85-9DL-GlutamineCAS 153-94-6D-TryptophanCAS 348-67-4D-MethionineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 328-38-1

What are the key identifiers for D-Leucine (CAS 328-38-1)?

D-Leucine is identified by CAS 328-38-1, with molecular formula C6H13NO2, molecular weight 131.17, InChIKey ROHFNLRQFUQHCH-RXMQYKEDSA-N.

Does CAS 328-38-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Large neutral amino acids transporter small subunit 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 328-38-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for D-Leucine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 328-38-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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