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Home/Compounds/CAS 35661-60-0
Formula C21H23NO4MW 353.4Research-use catalog entryCOA/SDS by request

Fmoc-leucine

CAS Number: 35661-60-0

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Loading RDKit molecule structure...
InChIKey: CBPJQFCAFFNICX-IBGZPJMESA-NC21H23NO4 | MW 353.4

Chemical Absolute Identifiers

CAS Number

35661-60-0

PubChem CID

1549133

Molecular Formula

C21H23NO4

Molecular Weight

353.4 g/mol

Exact Mass

353.162708

InChIKey

CBPJQFCAFFNICX-IBGZPJMESA-N

IUPAC Name

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid

SMILES String

CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Fmoc-leucine (CAS 35661-60-0) is listed in the Life Science portfolio, with molecular formula C21H23NO4 and molecular weight 353. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Amino Acid ResearchLife Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Sialin (Homo sapiens) — 6 assays; Nuclear factor erythroid 2-related factor 2 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Sialin

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 1 documents · best pChEMBL 4.99

Experimental evidence source: ChEMBL

Nuclear factor erythroid 2-related factor 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Fmoc-leucine

Names & Synonyms

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucinen-(fluorenyl-9-methoxycarbonyl)leucineN-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-leucineFmoc-L-leucineFmoc-Leu-OH
Show all synonyms
Fmoc-L-Leu-OHN-Fmoc-L-leucineN-(9-fluorenylmethoxycarbonyl)-L-leucine(((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpentanoic acid(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acidFmoc-L-LeuFMOC-LEUFmoc-N-Me-D-Nva-OHL-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-LEUCINE, N-((9H-FLUOREN-9-YLMETHOXY)CARBONYL)-Fmoc leucineN-Fmoc leucine
External Identifiers
EC NUMBER: 252-662-7DSSTOX SUBSTANCE ID: DTXSID0040751CHEMBL ID: CHEMBL149394UNII: KF18F70UF3WIKIDATA ID: Q27282223
Experimental Spectrum References
13C NMR Spectra — Sigma-Aldrich Co. LLC.1H NMR Spectra — Sigma-Aldrich Co. LLC.ATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Bio-Rad Laboratories, Inc.Raman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.bmcl.2023.129392Synthesis and evaluation of Fmoc-amino esters and amides bearing a substrate like quaternary ammonium group as selective butyrylcholinesterase inhibitors.PMID 37364726Synthesis and evaluation of Fmoc-amino esters and amides bearing a substrate like quaternary ammonium group as selective butyrylcholinesterase inhibitors.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1021/acs.jmedchem.9b02119Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(2R)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-4-methylpentanoic acidCAS 114360-54-2
Fmoc-L-aspartic acidCAS 119062-05-4
Fmoc-Phe-OH-13C9,15NCAS 1217455-27-0
Fmoc-L-Cys(SIT)-OHCAS 2545642-31-5
N-Fmoc-O-ethyl-D-homoserineCAS 2348338-16-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 114360-54-2(2R)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-4-methylpentanoic acidCAS 119062-05-4Fmoc-L-aspartic acidCAS 1217455-27-0Fmoc-Phe-OH-13C9,15NCAS 2545642-31-5Fmoc-L-Cys(SIT)-OHCAS 2348338-16-7N-Fmoc-O-ethyl-D-homoserineCAS 61-90-5L-LeucineCAS 82911-69-1N-(9-Fluorenylmethoxycarbonyloxy)succinimideCAS 28920-43-69-Fluorenylmethyl chloroformateCAS 100643-71-8DesloratadineCAS 10083-24-6Piceatannol

RFQ questions for CAS 35661-60-0

What are the key identifiers for Fmoc-leucine (CAS 35661-60-0)?

Fmoc-leucine is identified by CAS 35661-60-0, with molecular formula C21H23NO4, molecular weight 353.4, InChIKey CBPJQFCAFFNICX-IBGZPJMESA-N.

Does CAS 35661-60-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Sialin, Nuclear factor erythroid 2-related factor 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 35661-60-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Fmoc-leucine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 35661-60-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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