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Home/Compounds/CAS 62996-74-1
Formula C28H26N4O3MW 466.5Research-use catalog entryCOA/SDS by request

Staurosporine

CAS Number: 62996-74-1

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Loading RDKit molecule structure...
InChIKey: HKSZLNNOFSGOKW-FYTWVXJKSA-NC28H26N4O3 | MW 466.5

Chemical Absolute Identifiers

CAS Number

62996-74-1

PubChem CID

44259

Molecular Formula

C28H26N4O3

Molecular Weight

466.5 g/mol

Exact Mass

466.200491

InChIKey

HKSZLNNOFSGOKW-FYTWVXJKSA-N

IUPAC Name

(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

SMILES String

C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Staurosporine (CAS 62996-74-1) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C28H26N4O3 and molecular weight 466. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: STE20-like serine/threonine-protein kinase (Homo sapiens) — 8 assays; Serine/threonine-protein kinase 10 (Homo sapiens) — 9 assays; Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens) — 8 assays; Calcium/calmodulin-dependent protein kinase type II subunit alpha (Homo sapiens) — 7 assays; Calcium/calmodulin-dependent protein kinase kinase 1 (Homo sapiens) — 6 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

STE20-like serine/threonine-protein kinase

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 7 documents · best pChEMBL 10.7

Experimental evidence source: ChEMBL

Serine/threonine-protein kinase 10

Homo sapiens · SINGLE PROTEIN · 9 qualifying assays · 7 documents · best pChEMBL 10.52

Experimental evidence source: ChEMBL

Calcium/calmodulin-dependent protein kinase type II subunit delta

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 6 documents · best pChEMBL 10.51

Experimental evidence source: ChEMBL

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 6 documents · best pChEMBL 10.51

Experimental evidence source: ChEMBL

Calcium/calmodulin-dependent protein kinase kinase 1

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 5 documents · best pChEMBL 10.41

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

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Accidental Release

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For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Staurosporine

Names & Synonyms

StaurosporinAntibiotic 230Antibiotic AM 22828,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo(12.12.2.12,6.07,28.08,13.015,19.020,27.021,26)nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
Show all synonyms
1-((2R,3S,4S,6S)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo(12.12.2.12,6.07,28.08,13.015,19.020,27.021,26)nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl)-1-methylurea(+)-StaurosporineCCRIS 3272Alkaloid AM-2282 from Streptomyces(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one(5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-onemethoxy-methyl-(methylamino)[?]oneStaurosporin, 41nvr1stc1xbc1xjd1yhs
External Identifiers
EC NUMBER: 613-127-7DSSTOX SUBSTANCE ID: DTXSID6041131CHEMBL ID: CHEMBL388978CHEBI ID: CHEBI:15738UNII: H88EPA0A3NDRUGBANK ID: DB02010METABOLOMICS WORKBENCH ID: 182489NCI THESAURUS CODE: C1237PHARMGKB ID: PA165109623WIKIDATA ID: Q5957181
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.bmc.2021.116168Novel 4-(piperazin-1-yl)quinolin-2(1H)-one bearing thiazoles with antiproliferative activity through VEGFR-2-TK inhibition.DOI 10.1016/j.bmcl.2020.127740Design, synthesis and biological evaluation of novel 4-(pyrrolo[2,3-d]pyrimidine-4-yloxy)benzamide derivatives as potential antitumor agents.DOI 10.1016/j.bmcl.2021.128226Synthesis of novel 1H-Pyrazolo[3,4-b]pyridine derivatives as DYRK 1A/1B inhibitors.DOI 10.1016/j.bmcl.2021.128258Angiokinase inhibition of VEGFR-2, PDGFR and FGFR and cell growth inhibition in lung cancer: Design, synthesis, biological evaluation and molecular docking of novel azaheterocyclic coumarin derivatives.DOI 10.1016/j.ejmech.2020.112920Cytotoxic triterpenoid-safirinium conjugates target the endoplasmic reticulum.DOI 10.1016/j.ejmech.2020.112948Potent antiproliferative activity of bradykinin B2 receptor selective agonist FR-190997 and analogue structures thereof: A paradox resolved?DOI 10.1016/j.ejmech.2020.112994Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.DOI 10.1016/j.ejmech.2020.113003N-substituted benzimidazole acrylonitriles as in vitro tubulin polymerization inhibitors: Synthesis, biological activity and computational analysis.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

MidostaurinCAS 120685-11-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 571190-30-2PalbociclibCAS 120685-11-2MidostaurinCAS 443913-73-3VandetanibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 62996-74-1

What are the key identifiers for Staurosporine (CAS 62996-74-1)?

Staurosporine is identified by CAS 62996-74-1, with molecular formula C28H26N4O3, molecular weight 466.5, InChIKey HKSZLNNOFSGOKW-FYTWVXJKSA-N.

Does CAS 62996-74-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with STE20-like serine/threonine-protein kinase, Serine/threonine-protein kinase 10, Calcium/calmodulin-dependent protein kinase type II subunit delta, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase kinase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 62996-74-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Staurosporine?

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Is CAS 62996-74-1 available for quotation?

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