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Home/Compounds/CAS 745017-94-1
Formula C39H65N5O8MW 732Research-use catalog entryCOA/SDS by request

Monomethyl auristatin F

CAS Number: 745017-94-1

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Loading RDKit molecule structure...
InChIKey: MFRNYXJJRJQHNW-DEMKXPNLSA-NC39H65N5O8 | MW 732

Chemical Absolute Identifiers

CAS Number

745017-94-1

PubChem CID

10395173

Molecular Formula

C39H65N5O8

Molecular Weight

732 g/mol

Exact Mass

731.483314

InChIKey

MFRNYXJJRJQHNW-DEMKXPNLSA-N

IUPAC Name

(2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid

SMILES String

CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Monomethyl auristatin F (CAS 745017-94-1) is listed in the Life Science portfolio, with molecular formula C39H65N5O8 and molecular weight 732. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

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Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Monomethyl auristatin F

Names & Synonyms

MMAFMMAF peptideMonomethylauristatin FMMAF (GMP)MONOMETHYLAURISTATIN PHENYLALANINE
Show all synonyms
Mmaf (Monomethyl Auristatin F)MonomethylauristatinFMonoMethyl auristatin F (MMAF)L-PHENYLALANINE, N-METHYL-L-VALYL-L-VALYL-(3R,4S,5S)-3-METHOXY-5-METHYL-4-(METHYLAMINO)HEPTANOYL-(.ALPHA.R,.BETA.R,2S)-.BETA.-METHOXY-.ALPHA.-METHYL-2-PYRROLIDINEPROPANOYL-
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID601031563CHEMBL ID: CHEMBL3359822UNII: 1Z1AI9IW5LWIKIDATA ID: Q76415591
Literature & Patent References
DOI 10.1016/j.bmc.2024.117794Synthesis and anticancer properties of novel dolastatin 10 analogs featuring five-membered heterocyclic rings with a linkable group at the C-terminus.DOI 10.1016/j.ejmech.2024.116709Antibody-drug conjugates for targeted cancer therapy: Recent advances in potential payloads.PMID 38875875Synthesis and anticancer properties of novel dolastatin 10 analogs featuring five-membered heterocyclic rings with a linkable group at the C-terminus.PMID 39068862Antibody-drug conjugates for targeted cancer therapy: Recent advances in potential payloads.DOI 10.1021/acs.jnatprod.1c01135Discovery and Development of Dolastatin 10-Derived Antibody Drug Conjugate Anticancer Drugs.PMID 35072477Discovery and Development of Dolastatin 10-Derived Antibody Drug Conjugate Anticancer Drugs.DOI 10.1021/acsmedchemlett.1c00432Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization.PMID 34676042Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Auristatin FCAS 163768-50-1
Monomethylauristatin ECAS 474645-27-7
Demethyldolastatin 10CAS 203849-91-6
MafodotinCAS 863971-19-1
L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydro xy-1-methyl-CAS 160800-57-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 163768-50-1Auristatin FCAS 474645-27-7Monomethylauristatin ECAS 203849-91-6Demethyldolastatin 10CAS 863971-19-1MafodotinCAS 160800-57-7L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydro xy-1-methyl-CAS 13734-41-3Boc-L-ValineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 745017-94-1

What are the key identifiers for Monomethyl auristatin F (CAS 745017-94-1)?

Monomethyl auristatin F is identified by CAS 745017-94-1, with molecular formula C39H65N5O8, molecular weight 732, InChIKey MFRNYXJJRJQHNW-DEMKXPNLSA-N.

Can I request a COA for CAS 745017-94-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Monomethyl auristatin F?

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Is CAS 745017-94-1 available for quotation?

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