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Home/Compounds/CAS 81103-11-9
Formula C38H69NO13MW 748Research-use catalog entryCOA/SDS by request

Clarithromycin

CAS Number: 81103-11-9

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1 kg
Purity
98%
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5 g
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Loading RDKit molecule structure...
InChIKey: AGOYDEPGAOXOCK-KCBOHYOISA-NC38H69NO13 | MW 748

Chemical Absolute Identifiers

CAS Number

81103-11-9

PubChem CID

84029

Molecular Formula

C38H69NO13

Molecular Weight

748 g/mol

Exact Mass

747.476891

InChIKey

AGOYDEPGAOXOCK-KCBOHYOISA-N

IUPAC Name

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

SMILES String

CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O

Physical Properties

Appearance

Colorless needles from chloroform + diisopropyl ether (1:2) ... Also reported as crystals from ethanol

Melting Point

217–22 °C

pKa

8.99

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Clarithromycin (CAS 81103-11-9) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C38H69NO13 and molecular weight 748. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Solute carrier organic anion transporter family member 1B1 (Homo sapiens) — 3 assays; Solute carrier organic anion transporter family member 1B3 (Homo sapiens) — 3 assays; ATP-dependent translocase ABCB1 (Homo sapiens) — 10 assays; Voltage-gated inwardly rectifying potassium channel KCNH2 (Homo sapiens) — 6 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Solute carrier organic anion transporter family member 1B1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 5.51

Experimental evidence source: ChEMBL

Solute carrier organic anion transporter family member 1B3

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 5.48

Experimental evidence source: ChEMBL

ATP-dependent translocase ABCB1

Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 2 documents · best pChEMBL 5.42

Experimental evidence source: ChEMBL

Voltage-gated inwardly rectifying potassium channel KCNH2

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 5 documents · best pChEMBL 4.48

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Clarithromycin

Names & Synonyms

Biaxin6-O-MethylerythromycinKlaricidErythromycin, 6-O-methyl-Clarithromycine
Show all synonyms
6-O-Methylerythromycin aMacladinKlacidVeclamZeclarMavidNaxyClaritromicinaCyllindClarithromycinumBiaxin XLClarithromycin identityClarosipKlaricid XL
External Identifiers
EC NUMBER: 617-200-4EC NUMBER: 658-034-2DSSTOX SUBSTANCE ID: DTXSID3022829CHEMBL ID: CHEMBL1741CHEBI ID: CHEBI:3732UNII: H1250JIK0ADRUGBANK ID: DB01211HMDB ID: HMDB0015342KEGG ID: C06912KEGG ID: D00276METABOLOMICS WORKBENCH ID: 21286NCI THESAURUS CODE: C1054PHARMGKB ID: PA449028RXCUI: 21212WIKIDATA ID: Q118551Abbott-56268
Experimental Spectrum References
13C NMR SpectraATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral ResearchUV Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2025.117531Discovery of ultra short β-peptoids with selective activity against drug-resistant Mycobacterium tuberculosis.DOI 10.1021/acs.jmedchem.5c00112Real Way to Target Gram-Negative Pathogens: Discovery of a Novel &lt;i&gt;Helicobacter pylori&lt;/i&gt; Antibiotic Class.DOI 10.1021/acs.jnatprod.4c00834Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba &lt;i&gt;Balamuthia mandrillaris&lt;/i&gt;.DOI 10.1021/acsmedchemlett.5c00057Halogenated &lt;i&gt;N&lt;/i&gt;-Benzylbenzisoselenazolones Efficiently Inhibit &lt;i&gt;Helicobacter pylori&lt;/i&gt; Ureolysis &lt;i&gt;In Vitro&lt;/i&gt;.DOI 10.1039/D4MD00508BAdvances in antibacterial agents for <i>Mycobacterium fortuitum</i>.DOI 10.1039/D4MD00511BAzo derivatives of monoterpenes as anti-<i>Helicobacter pylori</i> agents: from synthesis to structure-based target investigation.PMID 39493226Advances in antibacterial agents for <i>Mycobacterium fortuitum</i>.PMID 39493229Azo derivatives of monoterpenes as anti-<i>Helicobacter pylori</i> agents: from synthesis to structure-based target investigation.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 114-07-8ErythromycinCAS 21829-25-4NifedipineCAS 22994-85-0BenznidazoleCAS 79794-75-5LoratadineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 81103-11-9

What are the key identifiers for Clarithromycin (CAS 81103-11-9)?

Clarithromycin is identified by CAS 81103-11-9, with molecular formula C38H69NO13, molecular weight 748, InChIKey AGOYDEPGAOXOCK-KCBOHYOISA-N.

Does CAS 81103-11-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Solute carrier organic anion transporter family member 1B1, Solute carrier organic anion transporter family member 1B3, ATP-dependent translocase ABCB1, Voltage-gated inwardly rectifying potassium channel KCNH2, Alpha-1A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 81103-11-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Clarithromycin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 81103-11-9 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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