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- Purity
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CAS Number: 841290-80-0
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CAS Number
841290-80-0
PubChem CID
11213558
Molecular Formula
C22H23FN6O5
Molecular Weight
470.5 g/mol
Exact Mass
470.171396
InChIKey
NHHQJBCNYHBUSI-UHFFFAOYSA-N
IUPAC Name
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
SMILES String
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Tamatinib (CAS 841290-80-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C22H23FN6O5 and molecular weight 470. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens) — 11 assays; Serine/threonine-protein kinase 16 (Homo sapiens) — 2 assays; Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens) — 10 assays; Mast/stem cell growth factor receptor Kit (Homo sapiens) — 9 assays; Platelet-derived growth factor receptor beta (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Receptor-type tyrosine-protein kinase FLT3
Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 5 documents · best pChEMBL 9.43
Experimental evidence source: ChEMBL
Serine/threonine-protein kinase 16
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.77
Experimental evidence source: ChEMBL
Proto-oncogene tyrosine-protein kinase receptor Ret
Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 6 documents · best pChEMBL 8.66
Experimental evidence source: ChEMBL
Mast/stem cell growth factor receptor Kit
Homo sapiens · SINGLE PROTEIN · 9 qualifying assays · 2 documents · best pChEMBL 8.6
Experimental evidence source: ChEMBL
Platelet-derived growth factor receptor beta
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.48
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Tamatinib is identified by CAS 841290-80-0, with molecular formula C22H23FN6O5, molecular weight 470.5, InChIKey NHHQJBCNYHBUSI-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Receptor-type tyrosine-protein kinase FLT3, Serine/threonine-protein kinase 16, Proto-oncogene tyrosine-protein kinase receptor Ret, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor beta. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
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