Ivacaftor
Preliminary reference disclaimer
This preliminary safety reference is generated from structured MolGraph catalog fields and public reference-style data. It is not a supplier-issued Safety Data Sheet and should not be used as a substitute for supplier-issued documentation, workplace safety review, transport classification, or regulatory compliance decisions. For supplier SDS or COA, submit a documentation request through MolGraph.
Preliminary safety reference
Available
Supplier-issued SDS
Available by request
COA
Available by RFQ / lot confirmation
Transport classification
Requires shipment review
CAS Number
873054-44-5
Chemical name
Ivacaftor
Molecular formula
C24H28N2O3
Molecular weight
392.5 g/mol
Synonyms
Kalydeco; N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide; ivacaftorum; ORKAMBI COMPONENT IVACAFTOR; SYMKEVI COMPONENT IVACAFTOR; TRIKAFTA COMPONENT IVACAFTOR; 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-; 3-Quinolinecarboxamide, N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-1,4-dihydro-4-oxo-; N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide; N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide; Elexacaftor, Tezacaftor, and Ivacaftor; Ivacaftor (VX-770)
InChIKey
PURKAOJPTOLRMP-UHFFFAOYSA-N
PubChem CID
16220172
Signal word
Warning
Catalog reference cue; confirm supplier documentation before use.
Hazard statements
H302, H315, H319, H335
Catalog reference cue; confirm supplier documentation before use.
Appearance
Solid
Catalog reference value; verify against supplier SDS before use.
pKa
11.08
Catalog reference value; verify against supplier SDS before use.
XLogP
5.6
Catalog reference value; verify against supplier SDS before use.
Shipment review
Shipment details require review before fulfillment.
Transport classification must be confirmed using supplier SDS and shipment documentation before dispatch.