4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-6-(trifluoromethyl)pyridine

4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-6-(trifluoromethyl)pyridine, identified by CAS 2223047-09-2, is a highly functionalized pyridine derivative. It features a chlorine atom, a trifluoromethyl group, and a pinacol boronate ester moiety. This compound serves as a versatile building block in organic synthesis, particularly for the construction of complex molecular architectures through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling. The trifluoromethyl group can impart distinct electronic and steric properties, while the boronate ester provides a reactive site for C-C bond formation, making it valuable for researchers in medicinal chemistry and materials science.

• Handle with appropriate personal protective equipment, including chemical-resistant gloves, safety glasses or goggles, and a lab coat. Ensure adequate ventilation or use a fume hood to prevent inhalation. Avoid direct contact with skin, eyes, and clothing. Do not ingest. Refer to the Safety Data Sheet (SDS) for comprehensive hazard information, first-aid measures, and safe handling, storage, and disposal procedures. Store in a cool, dry, and well-ventilated area, away from incompatible materials.