Active Chemical RecordCatalog PreviewCatalog ready

[6-Fluoro-5-(trifluoromethyl)pyridin-3-yl]boronic acid

CAS 2225175-78-8Formula C6H4BF4NO2MW 208.91PubChem 91882757

[6-Fluoro-5-(trifluoromethyl)pyridin-3-yl]boronic acid is a fluorinated pyridine derivative featuring a boronic acid group, making it a valuable building block for organic synthesis, particularly in cross-coupling reactions.

Loading RDKit molecule structure...
InChIKey: RNDWILSOANBHCY-UHFFFAOYSA-NC6H4BF4NO2 | MW 208.91

Chemical Identity

Molecular Formula

C6H4BF4NO2

Molecular Weight

208.91 g/mol

Exact Mass

209.027121

PubChem CID

91882757

IUPAC Name

[6-fluoro-5-(trifluoromethyl)-3-pyridinyl]boronic acid

SMILES String

OB(O)c1cnc(F)c(C(F)(F)F)c1

Names & Synonyms

(6-Fluoro-5-(trifluoromethyl)pyridin-3-yl)boronic acid6-fluoro-5-(trifluoromethyl)pyridin-3-ylboronic acid6-Fluoro-5-trifluoromethylpyridine-3-boronic acid
External Identifiers
CS-35007EN300-359542

Catalog Overview

This compound is a highly functionalized boronic acid, incorporating a pyridine ring substituted with both a fluorine atom and a trifluoromethyl group. The boronic acid moiety enables its use in various palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, for the efficient formation of carbon-carbon bonds. The presence of fluorine and trifluoromethyl groups can impart unique electronic, steric, and physicochemical properties to target molecules, making this intermediate particularly useful in the synthesis of novel pharmaceuticals, agrochemicals, and advanced materials for research purposes. It serves...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

This compound is a highly functionalized boronic acid, incorporating a pyridine ring substituted with both a fluorine atom and a trifluoromethyl group. The boronic acid moiety enables its use in various palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, for the efficient formation of carbon-carbon bonds. The presence of fluorine and trifluoromethyl groups can impart unique electronic, steric, and physicochemical properties to target molecules, making this intermediate particularly useful in the synthesis of novel pharmaceuticals, agrochemicals, and advanced materials for research purposes. It serves as a versatile tool for introducing complex fluorinated pyridine scaffolds into diverse chemical structures.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white powder

Physical State

Solid

Melting Point

145.0 °C

Boiling Point

280.0 °C

Density

1.5 g/cm³

Water Solubility

Slightly soluble

Flash Point

180.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Prevent skin and eye contact. Do not ingest. Store in a cool, dry place, away from incompatible materials. In case of exposure, seek immediate medical attention. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

1150114-63-8CAS 1150114-63-8
2657618-04-5CAS 2657618-04-5

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293339GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.