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[2-Fluoro-6-(trifluoromethyl)pyridin-4-YL]boronic acid

CAS 2256747-45-0Formula C6H4BF4NO2MW 208.91PubChem 72212951

[2-Fluoro-6-(trifluoromethyl)pyridin-4-YL]boronic acid is a functionalized boronic acid derivative featuring a fluorinated pyridine ring with a trifluoromethyl group, primarily used as a versatile intermediate in organic synthesis for research purposes.

Loading RDKit molecule structure...
InChIKey: XLLINGMQDWEGNC-UHFFFAOYSA-NC6H4BF4NO2 | MW 208.91

Chemical Identity

Molecular Formula

C6H4BF4NO2

Molecular Weight

208.91 g/mol

Exact Mass

209.027121

PubChem CID

72212951

IUPAC Name

[2-fluoro-6-(trifluoromethyl)-4-pyridinyl]boronic acid

SMILES String

OB(O)c1cc(F)nc(C(F)(F)F)c1

Names & Synonyms

(2-Fluoro-6-(trifluoromethyl)pyridin-4-yl)boronic acid2-FLUORO-6-(TRIFLUOROMETHYL)PYRIDINE-4-BORONIC ACID
External Identifiers
SCHEMBL29954732AB71360CS-29602EN300-24219703

Catalog Overview

[2-Fluoro-6-(trifluoromethyl)pyridin-4-YL]boronic acid, identified by CAS 2256747-45-0, is a valuable research-use chemical intermediate. It features a pyridine core substituted with a fluorine atom at position 2, a trifluoromethyl group at position 6, and a boronic acid moiety at position 4. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208. 91, this compound is characterized by its unique combination of halogen and boron functionalities.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

[2-Fluoro-6-(trifluoromethyl)pyridin-4-YL]boronic acid, identified by CAS 2256747-45-0, is a valuable research-use chemical intermediate. It features a pyridine core substituted with a fluorine atom at position 2, a trifluoromethyl group at position 6, and a boronic acid moiety at position 4. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208.91, this compound is characterized by its unique combination of halogen and boron functionalities. These features make it particularly useful in various cross-coupling reactions, such as Suzuki-Miyaura coupling, for the construction of complex organic molecules in medicinal chemistry and materials science research.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline powder

Physical State

Solid

Melting Point

150.0 °C

Boiling Point

280.0 °C

Density

1.5 g/cm³

Water Solubility

Slightly soluble

Flash Point

180.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • For research use only. Handle [2-Fluoro-6-(trifluoromethyl)pyridin-4-YL]boronic acid in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation, ingestion, and skin contact. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, away from incompatible materials.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

1150114-63-8CAS 1150114-63-8

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293190GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.