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Home/Compounds/CAS 1392275-56-7
Formula C46H62N12O14P2MW 1069Research-use catalog entryCOA/SDS by request

Tenofovir Alafenamide Fumarate

CAS Number: 1392275-56-7

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Loading RDKit molecule structure...
InChIKey: SVUJNSGGPUCLQZ-FQQAACOVSA-NC46H62N12O14P2 | MW 1069

Chemical Absolute Identifiers

CAS Number

1392275-56-7

PubChem CID

71492247

Molecular Formula

C46H62N12O14P2

Molecular Weight

1069 g/mol

Exact Mass

1068.398369

InChIKey

SVUJNSGGPUCLQZ-FQQAACOVSA-N

IUPAC Name

(E)-but-2-enedioic acid;bis(propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate)

SMILES String

CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)Oc1ccccc1.CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)Oc1ccccc1.O=C(O)/C=C/C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Tenofovir Alafenamide Fumarate (CAS 1392275-56-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C46H62N12O14P2 and molecular weight 1069. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Tenofovir Alafenamide Fumarate

Names & Synonyms

tenofovir alafenamide hemifumarateGS-7340 HemifumarateTENOFOVIR ALAFENAMIDE FUMARATE (2:1)TAFDESCOVY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE
Show all synonyms
ODEFSEY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATESYMTUZA COMPONENT TENOFOVIR ALAFENAMIDE FUMARATEBIKTARVY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE1-METHYLETHYL N-((S)-(((1R)-2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY)METHYL(PHENOXYPHOSPHINOYL)-L-ALANINATE, (2E)-2-BUTENEDIOATEbis(9-((2R,5S,7E)-2,7,10-trimethyl-5,8-dioxo-5-phenoxy-3,9-dioxa-6-aza-5lambda5-phosphaundecan-1-yl)-9H-purin-6-aminium) (2E)-but-2-enedioatebis(propan-2-yl N-((S)-((((2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate) (2E)-but-2-enedioatebis{9-[(2R,5S,7E)-2,7,10-trimethyl-5,8-dioxo-5-phenoxy-3,9-dioxa-6-aza-5lambda5-phosphaundecan-1-yl]-9H-purin-6-aminium} (2E)-but-2-enedioatebis{propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate} (2E)-but-2-enedioateL-Alanine, N-((S)-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinyl)-, 1-methylethyl ester, (2E)-2-butenedioate (2:1)L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (2:1)TENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF BIKTARVYTENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF DESCOVYTENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF GENVOYATENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF ODEFSEYTENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF SYMTUZA
External Identifiers
EC NUMBER: 805-448-8DSSTOX SUBSTANCE ID: DTXSID401027740CHEMBL ID: CHEMBL2364637CHEBI ID: CHEBI:90923UNII: FWF6Q91TZOKEGG ID: D10605NCI THESAURUS CODE: C152559RXCUI: 1721604WIKIDATA ID: Q27162911
Literature & Patent References
DOI 10.1016/j.ejmech.2023.116020Membrane-permeable tenofovir-di- and monophosphate analogues.PMID 38086193Membrane-permeable tenofovir-di- and monophosphate analogues.DOI 10.1021/acs.jmedchem.1c01444Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties.PMID 34713696Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Tenofovir AlafenamideCAS 379270-37-8
Phenyl hydrogen ((R)-1-(6-amino-9H-purin-9-YL)propan-2-yloxy)methylphosphonateCAS 379270-35-6
Tenofovir Disoproxil FumarateCAS 202138-50-9
Phosphonic acid, P-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, hydrate (1:1)CAS 206184-49-8
Diethyl P-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonateCAS 180587-75-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 379270-37-8Tenofovir AlafenamideCAS 379270-35-6Phenyl hydrogen ((R)-1-(6-amino-9H-purin-9-YL)propan-2-yloxy)methylphosphonateCAS 202138-50-9Tenofovir Disoproxil FumarateCAS 206184-49-8Phosphonic acid, P-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, hydrate (1:1)CAS 180587-75-1Diethyl P-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonateCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 1392275-56-7

What are the key identifiers for Tenofovir Alafenamide Fumarate (CAS 1392275-56-7)?

Tenofovir Alafenamide Fumarate is identified by CAS 1392275-56-7, with molecular formula C46H62N12O14P2, molecular weight 1069, InChIKey SVUJNSGGPUCLQZ-FQQAACOVSA-N.

Can I request a COA for CAS 1392275-56-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

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