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- Purity
- 98%
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CAS Number: 379270-37-8
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CAS Number
379270-37-8
PubChem CID
9574768
Molecular Formula
C21H29N6O5P
Molecular Weight
476.5 g/mol
Exact Mass
476.193705
InChIKey
LDEKQSIMHVQZJK-CAQYMETFSA-N
IUPAC Name
propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
SMILES String
CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)Oc1ccccc1
Melting Point
104–107 °C
Water Solubility
4.86 mol/L
pKa
3.96
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Tenofovir Alafenamide (CAS 379270-37-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C21H29N6O5P and molecular weight 476. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Lysosomal protective protein (Homo sapiens) — 3 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Lysosomal protective protein
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Protein deacetylase HDAC6
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Tenofovir Alafenamide is identified by CAS 379270-37-8, with molecular formula C21H29N6O5P, molecular weight 476.5, InChIKey LDEKQSIMHVQZJK-CAQYMETFSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Lysosomal protective protein, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
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