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Home/Compounds/CAS 229476-53-3
Formula C17H16BrN3O2MW 374.2Research-use catalog entryCOA/SDS by request

Ebe-A22

CAS Number: 229476-53-3

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Loading RDKit molecule structure...
InChIKey: IPWGDOZPSOZFOD-UHFFFAOYSA-NC17H16BrN3O2 | MW 374.2

Chemical Absolute Identifiers

CAS Number

229476-53-3

PubChem CID

5328227

Molecular Formula

C17H16BrN3O2

Molecular Weight

374.2 g/mol

Exact Mass

373.04259

InChIKey

IPWGDOZPSOZFOD-UHFFFAOYSA-N

IUPAC Name

N-(3-bromophenyl)-6,7-dimethoxy-N-methylquinazolin-4-amine

SMILES String

COc1cc2ncnc(N(C)c3cccc(Br)c3)c2cc1OC

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ebe-A22 (CAS 229476-53-3) is listed in the Advanced Chemicals portfolio, with molecular formula C17H16BrN3O2 and molecular weight 374. 20 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Epidermal growth factor receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Epidermal growth factor receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.82

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Ebe-A22

Names & Synonyms

4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-N-methyl-EBE-A 22Ranaconitine (>90%)EBE-A22?s6530
Show all synonyms
N-(3-bromophenyl)-6,7-dimethoxy-N-methyl-quinazolin-4-amine
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID60416148CHEMBL ID: CHEMBL447230WIKIDATA ID: Q82225322PD-153035-Me
Literature & Patent References
DOI 10.1016/j.bmcl.2011.01.137Impact of aryloxy-linked quinazolines: a novel series of selective VEGFR-2 receptor tyrosine kinase inhibitors.PMID 21353546Impact of aryloxy-linked quinazolines: a novel series of selective VEGFR-2 receptor tyrosine kinase inhibitors.DOI 10.1021/jm1009605Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives.PMID 21033670Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives.DOI 10.1021/jm9503613Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor.PMID 8568816Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

PD-153035CAS 153436-54-5
PD-153035 hydrochlorideCAS 183322-45-4
4-Chloro-6,7-dimethoxyquinazolineCAS 13790-39-1
6,7-Dimethoxyquinazolin-4-amineCAS 21575-13-3
6,7-dimethoxy-N-phenylquinazolin-4-amineCAS 21561-09-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 153436-54-5PD-153035CAS 183322-45-4PD-153035 hydrochlorideCAS 13790-39-14-Chloro-6,7-dimethoxyquinazolineCAS 21575-13-36,7-Dimethoxyquinazolin-4-amineCAS 21561-09-16,7-dimethoxy-N-phenylquinazolin-4-amineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 229476-53-3

What are the key identifiers for Ebe-A22 (CAS 229476-53-3)?

Ebe-A22 is identified by CAS 229476-53-3, with molecular formula C17H16BrN3O2, molecular weight 374.2, InChIKey IPWGDOZPSOZFOD-UHFFFAOYSA-N.

Does CAS 229476-53-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Epidermal growth factor receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 229476-53-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ebe-A22?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 229476-53-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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