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Home/Compounds/CAS 487-52-5
Formula C15H12O5MW 272.25Research-use catalog entryCOA/SDS by request

Butein

CAS Number: 487-52-5

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Loading RDKit molecule structure...
InChIKey: AYMYWHCQALZEGT-ORCRQEGFSA-NC15H12O5 | MW 272.25

Chemical Absolute Identifiers

CAS Number

487-52-5

PubChem CID

5281222

Molecular Formula

C15H12O5

Molecular Weight

272.25 g/mol

Exact Mass

272.068473

InChIKey

AYMYWHCQALZEGT-ORCRQEGFSA-N

IUPAC Name

(E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one

SMILES String

O=C(/C=C/c1ccc(O)c(O)c1)c1ccc(O)cc1O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Butein (CAS 487-52-5) is listed in the Advanced Chemicals portfolio, with molecular formula C15H12O5 and molecular weight 272. 25 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) — 2 assays; Enoyl-acyl-carrier protein reductase (Plasmodium falciparum) — 4 assays; Protein deacetylase HDAC6 (Homo sapiens) — 4 assays; Epidermal growth factor receptor (Homo sapiens) — 3 assays; Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Polyunsaturated fatty acid 5-lipoxygenase

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.34

Experimental evidence source: ChEMBL

Enoyl-acyl-carrier protein reductase

Plasmodium falciparum · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 7.85

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 5.67

Experimental evidence source: ChEMBL

Epidermal growth factor receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.1

Experimental evidence source: ChEMBL

Human immunodeficiency virus type 1 integrase

Human immunodeficiency virus 1 · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 4.7

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Butein

Names & Synonyms

2',3,4,4'-Tetrahydroxychalcone2',4',3,4-Tetrahydroxychalcone2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2',3,4,4'-Tetrahydroxy-chalcone3,4,2',4'-Tetrahydroxychalcone
Show all synonyms
(2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-oneChalcone, 2',3,4,4'-tetrahydroxy-(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one2',3,4,4'-tetrahydroxy Chalcone2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-Butein, solidButein (Standard)butein [M+H]+2,3,4,4-tetrahydroxy ChalconeAcrylophenone, 2',4'-dihydroxy-3-(3,4-dihydroxyphenyl)-3,4,2'',4''-tetrahydroxychalones8036(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-oneISOLIQUIRITIGENIN METABOLITE M4
External Identifiers
EC NUMBER: 207-659-5DSSTOX SUBSTANCE ID: DTXSID101025569CHEMBL ID: CHEMBL128000CHEBI ID: CHEBI:3237UNII: 4WVS5M0LGFKEGG ID: C08578METABOLOMICS WORKBENCH ID: 26587NCI THESAURUS CODE: C1028WIKIDATA ID: Q5002498
Experimental Spectrum References
13C NMR SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117008Multidrug-resistant bacteria quorum-sensing inhibitors: A particular focus on Pseudomonasaeruginosa.DOI 10.1021/acs.jmedchem.4c01116In Search for Inhibitors of Human Aldo-Keto Reductase 1B10 (AKR1B10) as Novel Agents to Fight Cancer and Chemoresistance: Current State-of-the-Art and Prospects.PMID 39500066Multidrug-resistant bacteria quorum-sensing inhibitors: A particular focus on Pseudomonasaeruginosa.PMID 39757466In Search for Inhibitors of Human Aldo-Keto Reductase 1B10 (AKR1B10) as Novel Agents to Fight Cancer and Chemoresistance: Current State-of-the-Art and Prospects.DOI 10.1016/j.bmc.2023.117561Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.DOI 10.1016/j.ejmech.2024.116836Discovery and optimization of isoliquiritigenin as a death-associated protein kinase 1 inhibitor.DOI 10.1039/d3md00713hA colorimetric assay adapted to fragment screening revealing aurones and chalcones as new arginase inhibitors.PMID 38157838Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

IsoliquiritigeninCAS 961-29-5
2',4'-DihydroxychalconeCAS 1776-30-3
2',4,4',6'-TetrahydroxychalconeCAS 73692-50-9
PiceatannolCAS 10083-24-6
IsobavachalconeCAS 20784-50-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 961-29-5IsoliquiritigeninCAS 1776-30-32',4'-DihydroxychalconeCAS 73692-50-92',4,4',6'-TetrahydroxychalconeCAS 10083-24-6PiceatannolCAS 20784-50-3IsobavachalconeCAS 1231929-97-7AbemaciclibCAS 146535-11-76,7-Dimethoxy-3-phenylquinoxalineCAS 211555-04-3Whi-P154CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid

RFQ questions for CAS 487-52-5

What are the key identifiers for Butein (CAS 487-52-5)?

Butein is identified by CAS 487-52-5, with molecular formula C15H12O5, molecular weight 272.25, InChIKey AYMYWHCQALZEGT-ORCRQEGFSA-N.

Does CAS 487-52-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Polyunsaturated fatty acid 5-lipoxygenase, Enoyl-acyl-carrier protein reductase, Protein deacetylase HDAC6, Epidermal growth factor receptor, Human immunodeficiency virus type 1 integrase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 487-52-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Butein?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 487-52-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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