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Home/Compounds/CAS 73692-50-9
Formula C15H12O5MW 272.25Research-use catalog entryCOA/SDS by request

2',4,4',6'-Tetrahydroxychalcone

CAS Number: 73692-50-9

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Loading RDKit molecule structure...
InChIKey: YQHMWTPYORBCMF-ZZXKWVIFSA-NC15H12O5 | MW 272.25

Chemical Absolute Identifiers

CAS Number

73692-50-9

PubChem CID

5280960

Molecular Formula

C15H12O5

Molecular Weight

272.25 g/mol

Exact Mass

272.068473

InChIKey

YQHMWTPYORBCMF-ZZXKWVIFSA-N

IUPAC Name

(E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one

SMILES String

C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2O)O)O)O

Physical Properties

Melting Point

184.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

2',4,4',6'-Tetrahydroxychalcone (CAS 73692-50-9) is listed in the Advanced Chemicals portfolio, with molecular formula C15H12O5 and molecular weight 272. 25 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Microtubule-associated protein tau (Homo sapiens) — 2 assays; Cytochrome P450 3A4 (Homo sapiens) — 2 assays; Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Microtubule-associated protein tau

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.1

Experimental evidence source: ChEMBL

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.1

Experimental evidence source: ChEMBL

Polyunsaturated fatty acid 5-lipoxygenase

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 4

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

2',4,4',6'-Tetrahydroxychalcone

Names & Synonyms

naringenin chalconeChalconaringeninIsosalipurpoltrans-2',4,4',6'-Tetrahydroxychalcone2'4'6'4-Tetrahydroxychalcone
Show all synonyms
3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-propen-1-one(2E)-3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-propen-1-one(E)-Naringenin chalconeChalcononaringenin(2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one2,4,4,6-tetrahydroxychalcone4,2,4,6-Tetrahydroxychalcone3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-oneChalcone, 2,4,4,6-tetrahydroxy-4,2',4',6'-TETRAHYDROXYCHALCONE2',4',6',4-tetrahydroxychalcone2-Propen-1-one, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, (2E)-Naringenin chalcone [M+H]+MEGxp0_001759
External Identifiers
EC NUMBER: 860-137-4DSSTOX SUBSTANCE ID: DTXSID101043553CHEMBL ID: CHEMBL338066CHEBI ID: CHEBI:15413UNII: YCF6Z24AS2HMDB ID: HMDB0029631KEGG ID: C06561METABOLOMICS WORKBENCH ID: 26740WIKIDATA ID: Q25098661
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2020.112649Synthesis of natural 3'-Prenylchalconaringenin and biological evaluation of ameliorating non-alcoholic fatty liver disease and metabolic syndrome.PMID 32791402Synthesis of natural 3'-Prenylchalconaringenin and biological evaluation of ameliorating non-alcoholic fatty liver disease and metabolic syndrome.DOI 10.1021/acs.jnatprod.8b00366In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.PMID 30688453In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.DOI 10.1016/j.ejmech.2017.02.007Analogues of xanthones--Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates.PMID 28242551Analogues of xanthones--Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates.DOI 10.1021/acs.jnatprod.5b00774Cytotoxic Evaluation against Breast Cancer Cells of Isoliquiritigenin Analogues from Spatholobus suberectus and Their Synthetic Derivatives.PMID 26690274Cytotoxic Evaluation against Breast Cancer Cells of Isoliquiritigenin Analogues from Spatholobus suberectus and Their Synthetic Derivatives.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Pinocembrin chalconeCAS 4197-97-1
IsoliquiritigeninCAS 961-29-5
2',4'-DihydroxychalconeCAS 1776-30-3
ButeinCAS 487-52-5
IsobavachalconeCAS 20784-50-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 4197-97-1Pinocembrin chalconeCAS 961-29-5IsoliquiritigeninCAS 1776-30-32',4'-DihydroxychalconeCAS 487-52-5ButeinCAS 20784-50-3IsobavachalconeCAS 60940-34-3EbselenCAS 117-89-5TrifluoperazineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 73692-50-9

What are the key identifiers for 2',4,4',6'-Tetrahydroxychalcone (CAS 73692-50-9)?

2',4,4',6'-Tetrahydroxychalcone is identified by CAS 73692-50-9, with molecular formula C15H12O5, molecular weight 272.25, InChIKey YQHMWTPYORBCMF-ZZXKWVIFSA-N.

Does CAS 73692-50-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Microtubule-associated protein tau, Cytochrome P450 3A4, Polyunsaturated fatty acid 5-lipoxygenase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 73692-50-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 2',4,4',6'-Tetrahydroxychalcone?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 73692-50-9 available for quotation?

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